Antibody data
- Antibody Data
- Antigen structure
- References [287]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- HRP-60004 - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#HRP-60004, RRID:AB_2737588
- Product name
- GAPDH antibody
- Antibody type
- Monoclonal
- Description
- GAPDH antibody (Cat. #HRP-60004) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, zebrafish, plant and has been validated for the following applications: WB.
- Reactivity
- Human, Mouse, Rat, Zebrafish
- Host
- Mouse
- Conjugate
- Horseradish Peroxidase
- Isotype
- IgG
- Antibody clone number
- 1E6D9
- Vial size
- 100ul
Submitted references CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway.
LRRK2 is required for CD38-mediated NAADP-Ca(2+) signaling and the downstream activation of TFEB (transcription factor EB) in immune cells.
Cell surface membrane lysosome-associated membrane glycoprotein 2 promotes cell adhesion via abundant N-glycans in choriocarcinoma.
Proteomic analysis of opossum Monodelphis domestica spinal cord reveals the changes of proteins related to neurodegenerative diseases during developmental period when neuroregeneration stops being possible.
Suhuang antitussive capsule ameliorates post-infectious cough in mice through AhR-Nrf2 pathway.
Paraoxonase 2 is an ER chaperone that regulates the epithelial Na+ channel.
Characteristics of the Gut Microbiome and IL-13/TGF-β1 Mediated Fibrosis in Post-Kasai Cholangitis of Biliary Atresia.
SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes.
Development and Validation of a Ferroptosis-Related Gene Signature for Overall Survival Prediction in Lung Adenocarcinoma.
WASp Is Crucial for the Unique Architecture of the Immunological Synapse in Germinal Center B-Cells.
Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules.
Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.
JNK Signaling Pathway Mediates Fluoride-Induced Upregulation of CK1α during Enamel Formation.
Tunicamycin-Induced Endoplasmic Reticulum Stress Promotes Breast Cancer Cell MDA-MB-231 Apoptosis through Inhibiting Wnt/β-Catenin Signaling Pathway.
miR-708 Negatively Regulates TNFα/IL-1β Signaling by Suppressing NF-κB and Arachidonic Acid Pathways.
Characterizing the distributions of IDO-1 expressing macrophages/microglia in human and murine brains and evaluating the immunological and physiological roles of IDO-1 in RAW264.7/BV-2 cells.
Valproic Acid Induces Autism-Like Synaptic and Behavioral Deficits by Disrupting Histone Acetylation of Prefrontal Cortex ALDH1A1 in Rats.
Carbon Monoxide Releasing Molecule-3 Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Carbon Monoxide Release.
Transgenic Mice Expressing Human α-Synuclein 1-103 Fragment as a Novel Model of Parkinson's Disease.
Bifidobacterium infantis Maintains Genome Stability in Ulcerative Colitis via Regulating Anaphase-Promoting Complex Subunit 7.
TAZ maintains telomere length in TNBC cells by mediating Rad51C expression.
PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice.
Discovery of Potent Antiallergic Agents Based on an o-Aminopyridinyl Alkynyl Scaffold.
HIV reprograms host m6Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
A CD10-OGP Membrane Peptolytic Signaling Axis in Fibroblasts Regulates Lipid Metabolism of Cancer Stem Cells via SCD1.
IKKε knockout alleviates angiotensin II-induced apoptosis and excessive autophagy in vascular smooth muscle cells by regulating the ERK1/2 pathway.
Porcine ZBED6 regulates growth of skeletal muscle and internal organs via multiple targets.
Direct targeting of amplified gene loci for proapoptotic anticancer therapy.
Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells.
Disrupting RhoA activity by blocking Arhgef3 expression mitigates microglia-induced neuroinflammation post spinal cord contusion.
Ubiquinol-cytochrome c reductase core protein 1 contributes to cardiac tolerance to acute exhaustive exercise.
Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage.
Effects of aging on the histology and biochemistry of rat tendon healing.
11βHSD2 Efficacy in Preventing Transcriptional Activation of the Mineralocorticoid Receptor by Corticosterone.
HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production.
Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer.
Highly Conserved C-Terminal Region of Indian Hedgehog N-Fragment Contributes to Its Auto-Processing and Multimer Formation.
Analyses of key mRNAs and lncRNAs for different osteo-differentiation potentials of periodontal ligament stem cell and gingival mesenchymal stem cell.
EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function.
Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.
TGF-β promote epithelial-mesenchymal transition via NF-κB/NOX4/ROS signal pathway in lung cancer cells.
Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation.
Erastin induces ferroptosis via ferroportin-mediated iron accumulation in endometriosis.
Mitochondrial activity regulates the differentiation of skin-derived mesenchymal stem cells into brown adipocytes to contribute to hypertension.
Development and Validation of High-Content Analysis for Screening HDAC6-Selective Inhibitors.
The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53.
A protein-fragment complementation assay reveals that celastrol and gambogic acid suppress ERα mutants in breast cancer.
An Ultra-Stable, Oxygen-Supply Nanoprobe Emitting in Near-Infrared-II Window to Guide and Enhance Radiotherapy by Promoting Anti-Tumor Immunity.
WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression.
Downregulation of Prolactin-Induced Protein Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells.
A single amino acid substitution in PRKDC is a determinant of sensitivity to Adriamycin-induced renal injury in mouse.
Decreased Expression and Uncoupling of Endothelial Nitric Oxide Synthase in the Cerebral Cortex of Rats with Thioacetamide-Induced Acute Liver Failure.
Identification of ARGLU1 as a potential therapeutic target for gastric cancer based on genome-wide functional screening data.
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.
Perturbation of astroglial Slc38 glutamine transporters by NH4 + contributes to neurophysiologic manifestations in acute liver failure.
Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer.
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases.
Rice Husk Silica Liquid Protects Pancreatic β Cells from Streptozotocin-Induced Oxidative Damage.
Hinokitiol Exhibits Antitumor Properties through Induction of ROS-Mediated Apoptosis and p53-Driven Cell-Cycle Arrest in Endometrial Cancer Cell Lines (Ishikawa, HEC-1A, KLE).
Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human.
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Defining the protein and lipid constituents of tubular recycling endosomes.
GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner.
Lipolytic gene DAGLA is targeted by miR-223 in chicken hepatocytes.
Maternal vitamin A deficiency impairs cholinergic and nitrergic neurons, leading to gastrointestinal dysfunction in rat offspring via RARβ.
Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model.
Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer.
Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof.
Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors.
Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats.
Halofuginone triggers a transcriptional program centered on ribosome biogenesis and function in honey bees.
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Ciclesonide activates glucocorticoid signaling in neonatal rat lung but does not trigger adverse effects in the cortex and cerebellum.
Transcriptomic analysis of tumor tissues and organoids reveals the crucial genes regulating the proliferation of lung adenocarcinoma.
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity.
Pretreatment with LCK inhibitors chemosensitizes cisplatin-resistant endometrioid ovarian tumors.
SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer.
The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma.
miR-3 Encoded by Hepatitis B Virus Downregulates PTEN Protein Expression and Promotes Cell Proliferation.
Electric field down-regulates CD9 to promote keratinocytes migration through AMPK pathway.
LRG1 promotes corneal angiogenesis and lymphangiogenesis in a corneal alkali burn mouse model.
Recombinant Dual-target MDM2/MDMX Inhibitor Reverses Doxorubicin Resistance through Activation of the TAB1/TAK1/p38 MAPK Pathway in Wild-type p53 Multidrug-resistant Breast Cancer Cells.
Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model.
Salidroside Attenuates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice and Modulates Inflammation of the Gut-Brain Axis.
Total Glycosides of Cistanche deserticola Promote Neurological Function Recovery by Inducing Neurovascular Regeneration via Nrf-2/Keap-1 Pathway in MCAO/R Rats.
Ubiquitin C-Terminal Hydrolase L5 (UCHL5) Accelerates the Growth of Endometrial Cancer via Activating the Wnt/β-Catenin Signaling Pathway.
Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria.
Oral Administration of Geranylgeraniol Rescues Denervation-induced Muscle Atrophy via Suppression of Atrogin-1.
FAM122A Inhibits Erythroid Differentiation through GATA1.
Non-canonical Fzd7 signaling contributes to breast cancer mesenchymal-like stemness involving Col6a1.
RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A.
CLPTM1L induces estrogen receptor β signaling-mediated radioresistance in non-small cell lung cancer cells.
High salt diet may promote progression of breast tumor through eliciting immune response.
Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model.
Physiology and Morphological Correlates of Excitatory Transmission are Preserved in Glutamine Transporter SN1-Depleted Mouse Frontal Cortex.
m(6) A RNA methyltransferases METTL3/14 regulate immune responses to anti-PD-1 therapy.
AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5.
Daily Oral Administration of Protease-Treated Royal Jelly Protects Against Denervation-Induced Skeletal Muscle Atrophy.
Endoplasmic Reticulum Stress Affects Cholesterol Homeostasis by Inhibiting LXRα Expression in Hepatocytes and Macrophages.
The beneficial effect of oyster peptides and oyster powder on cyclophosphamide-induced reproductive impairment in male rats: A comparative study.
Suppressor of Ty 16 promotes lung cancer malignancy and is negatively regulated by miR-1227-5p.
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation.
LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer.
Knockout of mouse receptor accessory protein 6 leads to sperm function and morphology defects†.
Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OA.
Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase.
Knockout of MMP3 Weakens Solid Tumor Organoids and Cancer Extracellular Vesicles.
SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP.
Exon 9-deleted CETP inhibits full length-CETP synthesis and promotes cellular triglyceride storage.
HJC0152 suppresses human non-small-cell lung cancer by inhibiting STAT3 and modulating metabolism.
Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ.
Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery.
Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade.
miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells.
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25.
Curcumin promotes osteogenic differentiation of periodontal ligament stem cells through the PI3K/AKT/Nrf2 signaling pathway.
HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Cathepsin L interacts with CDK2-AP1 as a potential predictor of prognosis in patients with breast cancer.
Metformin promotes osteogenic differentiation and protects against oxidative stress-induced damage in periodontal ligament stem cells via activation of the Akt/Nrf2 signaling pathway.
Glibenclamide ameliorates transplant-induced arteriosclerosis and inhibits macrophage migration and MCP-1 expression.
Calcium Channel α2δ1 Subunit Mediates Secondary Orofacial Hyperalgesia Through PKC-TRPA1/Gap Junction Signaling.
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Adenosine A2A receptor activation prevents DOCA-salt induced hypertensive cardiac remodeling via iBAT.
Apigenin attenuates pulmonary hypertension by inducing mitochondria-dependent apoptosis of PASMCs via inhibiting the hypoxia inducible factor 1α-KV1.5 channel pathway.
Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model.
Asparagine endopeptidase inhibitor protects against fenpropathrin-induced neurodegeneration via suppressing α-synuclein aggregation and neuroinflammation.
Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail.
PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS-driven cancer cells.
miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells.
Protocol for Site-Specific Photo-Crosslinking Proteomics to Identify Protein-Protein Interactions in Mammalian Cells.
PPARγ Deacetylation Confers the Antiatherogenic Effect and Improves Endothelial Function in Diabetes Treatment.
Inhibition of USP15 Prevent Glutamate-Induced Oxidative Damage by Activating Nrf2/HO-1 Signaling Pathway in HT22 Cells.
TNF‑α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR‑335‑5p.
Downregulation of GPR183 on infection restricts the early infection and intracellular replication of mycobacterium tuberculosis in macrophage.
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
STING expression in monocyte-derived macrophages is associated with the progression of liver inflammation and fibrosis in patients with nonalcoholic fatty liver disease.
Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer.
EphB4/ TNFR2/ERK/MAPK signaling pathway comprises a signaling axis to mediate the positive effect of TNF-α on osteogenic differentiation.
4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species.
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.
X-linked inhibitor of apoptosis protein accelerates migration by inducing epithelial-mesenchymal transition through TGF-β signaling pathway in esophageal cancer cells.
Roles for IFT172 and Primary Cilia in Cell Migration, Cell Division, and Neocortex Development.
Bcl-2 regulates pyroptosis and necroptosis by targeting BH3-like domains in GSDMD and MLKL.
SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes.
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
Pre-existing H4K16ac levels in euchromatin drive DNA repair by homologous recombination in S-phase.
CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17.
Long Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21.
Ten-Eleven Translocation (TET) Enzymes Modulate the Activation of Dendritic Cells in Allergic Rhinitis.
Suhuang Antitussive Capsules-Ameliorative Effects on LPS-Induced Sputum Obstruction in Mice Through Promoting HGF Secretion.
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death.
Nicotinic acetylcholine receptor subunit expression in the gastrocnemius and in the orbicularis oris before and after facial nerve injury in rats.
Different signalling in infarcted and non-infarcted areas of rat failing hearts: A role of necroptosis and inflammation.
Potential roles of lncRNA-Cox2 and EGR1 in regulating epidural fibrosis following laminectomy.
Regulation of the Metal Transporters ZIP14 and ZnT10 by Manganese Intake in Mice.
Simvastatin promotes endothelial dysfunction by activating the Wnt/β‑catenin pathway under oxidative stress.
Tissue-Resident Macrophages Promote Renal Cystic Disease.
Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.
Increased miRNA-518b inhibits trophoblast migration and angiogenesis by targeting EGR1 in early embryonic arrest†.
Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer.
Analyses of epithelial Na+ channel variants reveal that an extracellular β-ball domain critically regulates ENaC gating.
Study of chromatin remodeling genes implicates SMARCA4 as a putative player in oncogenesis in neuroblastoma.
MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium.
The mTOR-RUNX1 pathway regulates DC-SIGN expression in renal tubular epithelial cells.
Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration.
CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.
Tumor-Contacted Neutrophils Promote Metastasis by a CD90-TIMP-1 Juxtacrine-Paracrine Loop.
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Programmable RNA-Guided RNA Effector Proteins Built from Human Parts.
Sphingomyelin Synthase 2 Promotes Endothelial Dysfunction by Inducing Endoplasmic Reticulum Stress.
An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis.
Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area.
MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection.
Effect of 1α, 25-dihydroxyvitamin D3 on the osteogenic differentiation of human periodontal ligament stem cells and the underlying regulatory mechanism.
Persistent Overexposure to N-Methyl-D-Aspartate (NMDA) Calcium-Dependently Downregulates Glutamine Synthetase, Aquaporin 4, and Kir4.1 Channel in Mouse Cortical Astrocytes.
Spinal Serotonin 1A Receptor Contributes to the Analgesia of Acupoint Catgut Embedding by Inhibiting Phosphorylation of the N-Methyl-d-Aspartate Receptor GluN1 Subunit in Complete Freund's Adjuvant-Induced Inflammatory Pain in Rats.
Repurposing of mTOR Complex Inhibitors Attenuates MCL-1 and Sensitizes to PARP Inhibition.
PKP3 interactions with MAPK-JNK-ERK1/2-mTOR pathway regulates autophagy and invasion in ovarian cancer.
Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway.
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.
Potential ceRNA networks involved in autophagy suppression of pancreatic cancer caused by chloroquine diphosphate: A study based on differentially‑expressed circRNAs, lncRNAs, miRNAs and mRNAs.
MiR-552 promotes the proliferation, migration and EMT of hepatocellular carcinoma cells by inhibiting AJAP1 expression.
Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells.
Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer.
Murine PAIP1 stimulates translation of spermiogenic mRNAs stored by YBX2 via its interaction with YBX2†.
Rutin promotes the formation and osteogenic differentiation of human periodontal ligament stem cell sheets in vitro.
A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability.
Translation of yes-associated protein (YAP) was antagonized by its circular RNA via suppressing the assembly of the translation initiation machinery.
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription.
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Aggregatibacter actinomycetemcomitans Leukotoxin (LtxA) Requires Death Receptor Fas, in Addition to LFA-1, To Trigger Cell Death in T Lymphocytes.
Palmitoylation is required for TNF-R1 signaling.
PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
Mutations in topoisomerase IIβ result in a B cell immunodeficiency.
CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.
BP‑1‑102 exerts an antitumor effect on the AGS human gastric cancer cell line through modulating the STAT3 and MAPK signaling pathways.
Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production.
miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer.
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
FEZF1 is an Independent Predictive Factor for Recurrence and Promotes Cell Proliferation and Migration in Cervical Cancer.
Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer.
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
Decrease of Perivascular Adipose Tissue Browning Is Associated With Vascular Dysfunction in Spontaneous Hypertensive Rats During Aging.
Emblic Leafflower (Phyllanthus emblica L.) Fruits Ameliorate Vascular Smooth Muscle Cell Dysfunction in Hyperglycemia: An Underlying Mechanism Involved in Ellagitannin Metabolite Urolithin A.
The downregulation of WWOX induces epithelial-mesenchymal transition and enhances stemness and chemoresistance in breast cancer.
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21.
Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors.
The proliferation of colorectal cancer cells is suppressed by silencing of EIF3H.
Progranulin Is Positively Associated with Intervertebral Disc Degeneration by Interaction with IL-10 and IL-17 Through TNF Pathways.
Loss of miR-146b-3p Inhibits Perivascular Adipocyte Browning with Cold Exposure During Aging.
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages.
Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors.
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning.
After Treatment with Methylene Blue is Effective against Delayed Encephalopathy after Acute Carbon Monoxide Poisoning.
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
β1-Integrin Impacts Rad51 Stability and DNA Double-Strand Break Repair by Homologous Recombination.
hsa-miR-212 modulates the radiosensitivity of glioma cells by targeting BRCA1.
Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer.
miR-146a suppresses 5-lipoxygenase activating protein (FLAP) expression and Leukotriene B4 production in lung cancer cells.
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Elevated CRB3 expression suppresses breast cancer stemness by inhibiting β-catenin signalling to restore tamoxifen sensitivity.
Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells.
mfat-1 transgene protects cultured adult neural stem cells against cobalt chloride-mediated hypoxic injury by activating Nrf2/ARE pathways.
Morphological and molecular variations induce mitochondrial dysfunction as a possible underlying mechanism of athletic amenorrhea.
Tumor necrosis factor-alpha inhibits osteogenic differentiation of pre-osteoblasts by downregulation of EphB4 signaling via activated nuclear factor-kappaB signaling pathway.
CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness.
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
β-actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprograming.
An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo.
An In Vitro Comparative Study of Multisource Derived Human Mesenchymal Stem Cells for Bone Tissue Engineering.
Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats.
High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer.
AmotP130 regulates Rho GTPase and decreases breast cancer cell mobility.
The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.
A novel frameshift mutation in CX46 associated with hereditary dominant cataracts in a Chinese family.
Long non-coding RNA NEAT1 regulates permeability of the blood-tumor barrier via miR-181d-5p-mediated expression changes in ZO-1, occludin, and claudin-5.
miRNA-346 promotes proliferation, migration and invasion in liver cancer.
Generation of tryptophan hydroxylase 2 gene knockout pigs by CRISPR/Cas9-mediated gene targeting.
Isoliquiritigenin Induces Autophagy and Inhibits Ovarian Cancer Cell Growth.
Role of Nrf2 Signaling in the Regulation of Vascular BK Channel β1 Subunit Expression and BK Channel Function in High-Fat Diet-Induced Diabetic Mice.
p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Ammonia Reduces Intracellular Asymmetric Dimethylarginine in Cultured Astrocytes Stimulating Its y⁺LAT2 Carrier-Mediated Loss.
Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial-mesenchymal transition and PI3K/Akt/GSK3β activation.
Neuronal ELAVL proteins utilize AUF-1 as a co-partner to induce neuron-specific alternative splicing of APP.
Tris (1,3-dichloro-2-propyl) phosphate induces toxicity by stimulating CaMK2 in PC12 cells.
MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer.
Low expression of PinX1 is associated with malignant behavior in basal-like breast cancer.
Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity.
The transcription factor RFX5 is a transcriptional activator of the TPP1 gene in hepatocellular carcinoma.
Correspondence: Assessment of learning, memory and attention in developmental neurotoxicology.
Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish.
Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway.
N-acetylcysteine ameliorates repetitive/stereotypic behavior due to its antioxidant properties without activation of the canonical Wnt pathway in a valproic acid-induced rat model of autism.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin.
Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro.
Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice.
Eupolyphaga sinensis Walker Ethanol Extract Suppresses Cell Growth and Invasion in Human Breast Cancer Cells.
System N transporters are critical for glutamine release and modulate metabolic fluxes of glucose and acetate in cultured cortical astrocytes: changes induced by ammonia.
c-Myc plays a key role in TADs-induced apoptosis and cell cycle arrest in human hepatocellular carcinoma cells.
Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation.
miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program.
Taspine derivative TAS9 regulates cell growth and metastasis of human hepatocellular carcinoma.
Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway.
Cell polarity protein CRB3 is an independent favorable prognostic factor for clear cell renal cell carcinoma.
Elabela-apelin receptor signaling pathway is functional in mammalian systems.
Momordica cochinchinensis seed extracts suppress migration and invasion of human breast cancer ZR-75-30 cells via down-regulating MMP-2 and MMP-9.
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling.
Huang C, Du R, Jia X, Liu K, Qiao Y, Wu Q, Yao N, Yang L, Zhou L, Liu X, Xiang P, Xin M, Wang Y, Chen X, Kim DJ, Dong Z, Li X
Cell death and differentiation 2022 Jan;29(1):14-27
Cell death and differentiation 2022 Jan;29(1):14-27
LRRK2 is required for CD38-mediated NAADP-Ca(2+) signaling and the downstream activation of TFEB (transcription factor EB) in immune cells.
Nabar NR, Heijjer CN, Shi CS, Hwang IY, Ganesan S, Karlsson MCI, Kehrl JH
Autophagy 2022 Jan;18(1):204-222
Autophagy 2022 Jan;18(1):204-222
Cell surface membrane lysosome-associated membrane glycoprotein 2 promotes cell adhesion via abundant N-glycans in choriocarcinoma.
Nishino K, Nishiko Y, Shibata M, Oda Y, Watanabe E, Niimi K, Yamamoto E, Kajiyama H
Placenta 2022 Jan;117:109-117
Placenta 2022 Jan;117:109-117
Proteomic analysis of opossum Monodelphis domestica spinal cord reveals the changes of proteins related to neurodegenerative diseases during developmental period when neuroregeneration stops being possible.
Tomljanović I, Petrović A, Ban J, Mladinic M
Biochemical and biophysical research communications 2022 Jan 8;587:85-91
Biochemical and biophysical research communications 2022 Jan 8;587:85-91
Suhuang antitussive capsule ameliorates post-infectious cough in mice through AhR-Nrf2 pathway.
Liang R, Tong X, Dong Z, Qin W, Fan L, Bai Z, Zhang Z, Xiang T, Wang Z, Tan N
Journal of ethnopharmacology 2022 Jan 30;283:114664
Journal of ethnopharmacology 2022 Jan 30;283:114664
Paraoxonase 2 is an ER chaperone that regulates the epithelial Na+ channel.
Shi S, Buck TM, Nickerson AJ, Brodsky JL, Kleyman TR
American journal of physiology. Cell physiology 2022 Jan 1;322(1):C111-C121
American journal of physiology. Cell physiology 2022 Jan 1;322(1):C111-C121
Characteristics of the Gut Microbiome and IL-13/TGF-β1 Mediated Fibrosis in Post-Kasai Cholangitis of Biliary Atresia.
Meng L, Liu J, Wang J, Du M, Zhang S, Huang Y, Shen Z, Dong R, Chen G, Zheng S
Frontiers in pediatrics 2021;9:751204
Frontiers in pediatrics 2021;9:751204
SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes.
Giordano I, Pirone L, Muratore V, Landaluze E, Pérez C, Lang V, Garde-Lapido E, Gonzalez-Lopez M, Barroso-Gomila O, Vertegaal ACO, Aransay AM, Rodriguez JA, Rodriguez MS, Sutherland JD, Barrio R
Frontiers in cell and developmental biology 2021;9:715868
Frontiers in cell and developmental biology 2021;9:715868
Development and Validation of a Ferroptosis-Related Gene Signature for Overall Survival Prediction in Lung Adenocarcinoma.
Tian Q, Zhou Y, Zhu L, Gao H, Yang J
Frontiers in cell and developmental biology 2021;9:684259
Frontiers in cell and developmental biology 2021;9:684259
WASp Is Crucial for the Unique Architecture of the Immunological Synapse in Germinal Center B-Cells.
Li Y, Bhanja A, Upadhyaya A, Zhao X, Song W
Frontiers in cell and developmental biology 2021;9:646077
Frontiers in cell and developmental biology 2021;9:646077
Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.
Xu R, Kang L, Wei S, Yang C, Fu Y, Ding Z, Zou Y
Frontiers in cardiovascular medicine 2021;8:748156
Frontiers in cardiovascular medicine 2021;8:748156
SIX1 Activation Is Involved in Cell Proliferation, Migration, and Anti-inflammation of Acute Ischemia/Reperfusion Injury in Mice.
Jin Y, Zhang M, Li M, Zhang H, Zhao L, Qian C, Li S, Zhang H, Gao M, Pan B, Li R, Wan X, Cao C
Frontiers in molecular biosciences 2021;8:725319
Frontiers in molecular biosciences 2021;8:725319
Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules.
Messerschmidt VL, Chintapula U, Kuriakose AE, Laboy S, Truong TTD, Kydd LA, Jaworski J, Pan Z, Sadek H, Nguyen KT, Lee J
Frontiers in cardiovascular medicine 2021;8:707897
Frontiers in cardiovascular medicine 2021;8:707897
Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.
Pan B, Zhang H, Hong Y, Ma M, Wan X, Cao C
Gerontology 2021;67(5):611-619
Gerontology 2021;67(5):611-619
JNK Signaling Pathway Mediates Fluoride-Induced Upregulation of CK1α during Enamel Formation.
Yang Z, Shi G, Guo J, Zhou Y, Jia J
Caries research 2021;55(3):225-233
Caries research 2021;55(3):225-233
Tunicamycin-Induced Endoplasmic Reticulum Stress Promotes Breast Cancer Cell MDA-MB-231 Apoptosis through Inhibiting Wnt/β-Catenin Signaling Pathway.
You Z, He L, Yan N
Journal of healthcare engineering 2021;2021:6394514
Journal of healthcare engineering 2021;2021:6394514
miR-708 Negatively Regulates TNFα/IL-1β Signaling by Suppressing NF-κB and Arachidonic Acid Pathways.
Monteleone NJ, Lutz CS
Mediators of inflammation 2021;2021:5595520
Mediators of inflammation 2021;2021:5595520
Characterizing the distributions of IDO-1 expressing macrophages/microglia in human and murine brains and evaluating the immunological and physiological roles of IDO-1 in RAW264.7/BV-2 cells.
Ji R, Ma L, Chen X, Sun R, Zhang L, Saiyin H, Wei W
PloS one 2021;16(11):e0258204
PloS one 2021;16(11):e0258204
Valproic Acid Induces Autism-Like Synaptic and Behavioral Deficits by Disrupting Histone Acetylation of Prefrontal Cortex ALDH1A1 in Rats.
Liu H, Tan M, Cheng B, Wang S, Xiao L, Zhu J, Wu Q, Lai X, Zhang Q, Chen J, Li T
Frontiers in neuroscience 2021;15:641284
Frontiers in neuroscience 2021;15:641284
Carbon Monoxide Releasing Molecule-3 Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Carbon Monoxide Release.
Chen H, Dai Y, Cui J, Yin X, Feng W, Lv M, Song H
Drug design, development and therapy 2021;15:1691-1704
Drug design, development and therapy 2021;15:1691-1704
Transgenic Mice Expressing Human α-Synuclein 1-103 Fragment as a Novel Model of Parkinson's Disease.
Tian Y, He M, Pan L, Yuan X, Xiong M, Meng L, Yao Z, Yu Z, Ye K, Zhang Z
Frontiers in aging neuroscience 2021;13:760781
Frontiers in aging neuroscience 2021;13:760781
Bifidobacterium infantis Maintains Genome Stability in Ulcerative Colitis via Regulating Anaphase-Promoting Complex Subunit 7.
Han T, Hu X, Li K, Zhang D, Zhang Y, Li J
Frontiers in microbiology 2021;12:761113
Frontiers in microbiology 2021;12:761113
TAZ maintains telomere length in TNBC cells by mediating Rad51C expression.
Yang L, Wang B, Jiao X, Zhou C, Chen S, Gao X, Sun W, Song S, Li J, Liu J, Wang Y, Liu P
Breast cancer research : BCR 2021 Sep 6;23(1):89
Breast cancer research : BCR 2021 Sep 6;23(1):89
PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice.
Cheng YW, Zhang ZB, Lan BD, Lin JR, Chen XH, Kong LR, Xu L, Ruan CC, Gao PJ
The Journal of experimental medicine 2021 Sep 6;218(9)
The Journal of experimental medicine 2021 Sep 6;218(9)
Discovery of Potent Antiallergic Agents Based on an o-Aminopyridinyl Alkynyl Scaffold.
Xie Z, Xiang C, Li X, Fan C, Chen T, Liu M, Ma Y, Bai F, Tang W, Hu Y
Journal of medicinal chemistry 2021 Sep 23;64(18):13588-13603
Journal of medicinal chemistry 2021 Sep 23;64(18):13588-13603
HIV reprograms host m6Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
Zhang Q, Kang Y, Wang S, Gonzalez GM, Li W, Hui H, Wang Y, Rana TM
Nature communications 2021 Sep 20;12(1):5543
Nature communications 2021 Sep 20;12(1):5543
A CD10-OGP Membrane Peptolytic Signaling Axis in Fibroblasts Regulates Lipid Metabolism of Cancer Stem Cells via SCD1.
Yu S, Lu Y, Su A, Chen J, Li J, Zhou B, Liu X, Xia Q, Li Y, Li J, Huang M, Ye Y, Zhao Q, Jiang S, Yan X, Wang X, Di C, Pan J, Su S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Oct;8(19):e2101848
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Oct;8(19):e2101848
IKKε knockout alleviates angiotensin II-induced apoptosis and excessive autophagy in vascular smooth muscle cells by regulating the ERK1/2 pathway.
Chen G, Xu Y, Yao Y, Cao Y, Liu Y, Chai H, Chen W, Chen X
Experimental and therapeutic medicine 2021 Oct;22(4):1051
Experimental and therapeutic medicine 2021 Oct;22(4):1051
Porcine ZBED6 regulates growth of skeletal muscle and internal organs via multiple targets.
Wang D, Pan D, Xie B, Wang S, Xing X, Liu X, Ma Y, Andersson L, Wu J, Jiang L
PLoS genetics 2021 Oct;17(10):e1009862
PLoS genetics 2021 Oct;17(10):e1009862
Direct targeting of amplified gene loci for proapoptotic anticancer therapy.
Kaushik Tiwari M, Colon-Rios DA, Tumu HCR, Liu Y, Quijano E, Krysztofiak A, Chan C, Song E, Braddock DT, Suh HW, Saltzman WM, Rogers FA
Nature biotechnology 2021 Oct 28;
Nature biotechnology 2021 Oct 28;
Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells.
Kwok HH, Gao B, Chan KH, Ip MS, Minna JD, Lam DC
Cancers 2021 Oct 25;13(21)
Cancers 2021 Oct 25;13(21)
Disrupting RhoA activity by blocking Arhgef3 expression mitigates microglia-induced neuroinflammation post spinal cord contusion.
Liao L, Qian ZY, Li XY, Yang DS, Lei BJ, Li HJ, Hong X
Journal of neuroimmunology 2021 Oct 15;359:577688
Journal of neuroimmunology 2021 Oct 15;359:577688
Ubiquinol-cytochrome c reductase core protein 1 contributes to cardiac tolerance to acute exhaustive exercise.
Yi T, Chen H, Zhan J, Li Y, Long Z, Wu Z, Yang M, Peng T, Li H
Experimental biology and medicine (Maywood, N.J.) 2021 Oct 14;:15353702211046546
Experimental biology and medicine (Maywood, N.J.) 2021 Oct 14;:15353702211046546
Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage.
Kaneko T, Horiuchi K, Chijimatsu R, Mori D, Nagata K, Omata Y, Yano F, Inui H, Moro T, Tanaka S, Saito T
Journal of bone and mineral metabolism 2021 Nov 9;
Journal of bone and mineral metabolism 2021 Nov 9;
Effects of aging on the histology and biochemistry of rat tendon healing.
Lai F, Tang H, Wang J, Lu K, Bian X, Wang Y, Shi Y, Guo Y, He G, Zhou M, Zhang X, Zhou B, Zhang J, Chen W, Tang K
BMC musculoskeletal disorders 2021 Nov 15;22(1):949
BMC musculoskeletal disorders 2021 Nov 15;22(1):949
11βHSD2 Efficacy in Preventing Transcriptional Activation of the Mineralocorticoid Receptor by Corticosterone.
Ali Y, Kuppusamy M, Velarde-Miranda C, Gomez-Sanchez CM, Plonczynski M, Gomez-Sanchez CE, Gomez-Sanchez EP
Journal of the Endocrine Society 2021 Nov 1;5(11):bvab146
Journal of the Endocrine Society 2021 Nov 1;5(11):bvab146
HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production.
Wang J, Chen Y, Zeng Z, Feng R, Wang Q, Zhang Q, Sun K, Chen AF, Lu Y, Yu Y
Experimental cell research 2021 Nov 1;408(1):112831
Experimental cell research 2021 Nov 1;408(1):112831
Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer.
Zhang Z, Xu Y, Zhao C
Cancer medicine 2021 May;10(10):3332-3345
Cancer medicine 2021 May;10(10):3332-3345
Highly Conserved C-Terminal Region of Indian Hedgehog N-Fragment Contributes to Its Auto-Processing and Multimer Formation.
Wang X, Liu H, Liu Y, Han G, Wang Y, Chen H, He L, Ma G
Biomolecules 2021 May 25;11(6)
Biomolecules 2021 May 25;11(6)
Analyses of key mRNAs and lncRNAs for different osteo-differentiation potentials of periodontal ligament stem cell and gingival mesenchymal stem cell.
Jia L, Zhang Y, Li D, Zhang W, Zhang D, Xu X
Journal of cellular and molecular medicine 2021 May 24;
Journal of cellular and molecular medicine 2021 May 24;
EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function.
Bahl S, Ling H, Acharige NPN, Santos-Barriopedro I, Pflum MKH, Seto E
Cell death & disease 2021 May 11;12(5):469
Cell death & disease 2021 May 11;12(5):469
Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.
Qin W, Tong X, Liang R, Tang K, Wu X, Jia Y, Tan N
Journal of ethnopharmacology 2021 May 10;271:113827
Journal of ethnopharmacology 2021 May 10;271:113827
TGF-β promote epithelial-mesenchymal transition via NF-κB/NOX4/ROS signal pathway in lung cancer cells.
Ma M, Shi F, Zhai R, Wang H, Li K, Xu C, Yao W, Zhou F
Molecular biology reports 2021 Mar;48(3):2365-2375
Molecular biology reports 2021 Mar;48(3):2365-2375
Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation.
Heck AL, Mishra S, Prenzel T, Feulner L, Achhammer E, Särchen V, Blagg BSJ, Schneider-Brachert W, Schütze S, Fritsch J
Immunobiology 2021 Mar;226(2):152070
Immunobiology 2021 Mar;226(2):152070
Erastin induces ferroptosis via ferroportin-mediated iron accumulation in endometriosis.
Li Y, Zeng X, Lu D, Yin M, Shan M, Gao Y
Human reproduction (Oxford, England) 2021 Mar 18;36(4):951-964
Human reproduction (Oxford, England) 2021 Mar 18;36(4):951-964
Mitochondrial activity regulates the differentiation of skin-derived mesenchymal stem cells into brown adipocytes to contribute to hypertension.
Xi W, Chen W, Sun W, Li X, Suo Z, Jiang G, Gao P, Li Q
Stem cell research & therapy 2021 Mar 10;12(1):167
Stem cell research & therapy 2021 Mar 10;12(1):167
Development and Validation of High-Content Analysis for Screening HDAC6-Selective Inhibitors.
Nong Y, Hou Y, Pu Y, Li S, Lan Y
SLAS discovery : advancing life sciences R & D 2021 Jun;26(5):628-641
SLAS discovery : advancing life sciences R & D 2021 Jun;26(5):628-641
The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53.
Yi JS, Sias-Garcia O, Nasholm N, Hu X, Iniguez AB, Hall MD, Davis M, Guha R, Moreno-Smith M, Barbieri E, Duong K, Koach J, Qi J, Bradner JE, Stegmaier K, Weiss WA, Gustafson WC
Neoplasia (New York, N.Y.) 2021 Jun;23(6):624-633
Neoplasia (New York, N.Y.) 2021 Jun;23(6):624-633
A protein-fragment complementation assay reveals that celastrol and gambogic acid suppress ERα mutants in breast cancer.
Liu X, Hu Q, Wang W, Ma H, Pu J, Cui J, Gong T, Wu Y, Lu W, Huang J
Biochemical pharmacology 2021 Jun;188:114583
Biochemical pharmacology 2021 Jun;188:114583
An Ultra-Stable, Oxygen-Supply Nanoprobe Emitting in Near-Infrared-II Window to Guide and Enhance Radiotherapy by Promoting Anti-Tumor Immunity.
Wang M, Li H, Huang B, Chen S, Cui R, Sun ZJ, Zhang M, Sun T
Advanced healthcare materials 2021 Jun;10(12):e2100090
Advanced healthcare materials 2021 Jun;10(12):e2100090
WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression.
Wu M, Xia X, Hu J, Fowlkes NW, Li S
Nature communications 2021 Jun 9;12(1):3500
Nature communications 2021 Jun 9;12(1):3500
Downregulation of Prolactin-Induced Protein Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells.
Li X, Zhang Y, Jia L, Xing Y, Zhao B, Sui L, Liu D, Xu X
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 7;27:e930610
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 7;27:e930610
A single amino acid substitution in PRKDC is a determinant of sensitivity to Adriamycin-induced renal injury in mouse.
Watanabe M, Takahashi Y, Hiura K, Nakano K, Okamura T, Sasaki H, Sasaki N
Biochemical and biophysical research communications 2021 Jun 4;556:121-126
Biochemical and biophysical research communications 2021 Jun 4;556:121-126
Decreased Expression and Uncoupling of Endothelial Nitric Oxide Synthase in the Cerebral Cortex of Rats with Thioacetamide-Induced Acute Liver Failure.
Milewski K, Czarnecka AM, Albrecht J, Zielińska M
International journal of molecular sciences 2021 Jun 22;22(13)
International journal of molecular sciences 2021 Jun 22;22(13)
Identification of ARGLU1 as a potential therapeutic target for gastric cancer based on genome-wide functional screening data.
Li F, Li J, Yu J, Pan T, Yu B, Sang Q, Dai W, Hou J, Yan C, Zang M, Zhu Z, Su L, Li YY, Liu B
EBioMedicine 2021 Jul;69:103436
EBioMedicine 2021 Jul;69:103436
DHCR24 Knockdown Lead to Hyperphosphorylation of Tau at Thr181, Thr231, Ser262, Ser396, and Ser422 Sites by Membrane Lipid-Raft Dependent PP2A Signaling in SH-SY5Y Cells.
Qi Z, Zhang Y, Yao K, Zhang M, Xu Y, Zhang J, Bai X, Zu H
Neurochemical research 2021 Jul;46(7):1627-1640
Neurochemical research 2021 Jul;46(7):1627-1640
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer.
Wang JZ, Zhu W, Han J, Yang X, Zhou R, Lu HC, Yu H, Yuan WB, Li PC, Tao J, Lu Q, Wei JF, Yang H
Cancer communications (London, England) 2021 Jul;41(7):560-575
Cancer communications (London, England) 2021 Jul;41(7):560-575
Perturbation of astroglial Slc38 glutamine transporters by NH4 + contributes to neurophysiologic manifestations in acute liver failure.
Hamdani EH, Popek M, Frontczak-Baniewicz M, Utheim TP, Albrecht J, Zielińska M, Chaudhry FA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jul;35(7):e21588
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jul;35(7):e21588
Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer.
Huang D, Chen X, Zeng X, Lao L, Li J, Xing Y, Lu Y, Ouyang Q, Chen J, Yang L, Su F, Yao H, Liu Q, Su S, Song E
Nature immunology 2021 Jul;22(7):865-879
Nature immunology 2021 Jul;22(7):865-879
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases.
Zhang N, Bewick B, Schultz J, Tiwari A, Krencik R, Zhang A, Adachi K, Xia G, Yun K, Sarkar P, Ashizawa T
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Jul;18(3):1710-1728
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2021 Jul;18(3):1710-1728
Rice Husk Silica Liquid Protects Pancreatic β Cells from Streptozotocin-Induced Oxidative Damage.
Chen HY, Chiang YF, Wang KL, Huang TC, Ali M, Shieh TM, Chang HY, Hong YH, Hsia SM
Antioxidants (Basel, Switzerland) 2021 Jul 5;10(7)
Antioxidants (Basel, Switzerland) 2021 Jul 5;10(7)
Hinokitiol Exhibits Antitumor Properties through Induction of ROS-Mediated Apoptosis and p53-Driven Cell-Cycle Arrest in Endometrial Cancer Cell Lines (Ishikawa, HEC-1A, KLE).
Chen HY, Cheng WP, Chiang YF, Hong YH, Ali M, Huang TC, Wang KL, Shieh TM, Chang HY, Hsia SM
International journal of molecular sciences 2021 Jul 31;22(15)
International journal of molecular sciences 2021 Jul 31;22(15)
Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human.
Chijimatsu R, Miwa S, Okamura G, Miyahara J, Tachibana N, Ishikura H, Higuchi J, Maenohara Y, Tsuji S, Sameshima S, Takagi K, Nakazato K, Kawaguchi K, Yamagami R, Inui H, Taketomi S, Tanaka S, Saito T
Stem cell research & therapy 2021 Jul 15;12(1):405
Stem cell research & therapy 2021 Jul 15;12(1):405
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Chen H, Qian Z, Zhang S, Tang J, Fang L, Jiang F, Ge D, Chang J, Cao J, Yang L, Cao X
Redox biology 2021 Jan;38:101774
Redox biology 2021 Jan;38:101774
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
Journal of inorganic biochemistry 2021 Jan;214:111269
Journal of inorganic biochemistry 2021 Jan;214:111269
Defining the protein and lipid constituents of tubular recycling endosomes.
Farmer T, Xie S, Naslavsky N, Stöckli J, James DE, Caplan S
The Journal of biological chemistry 2021 Jan-Jun;296:100190
The Journal of biological chemistry 2021 Jan-Jun;296:100190
GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner.
Xia Z, Zhang X, Liu P, Zhang R, Huang Z, Li D, Xiao X, Wu M, Ning N, Zhang Q, Zhang J, Liu M, Jiao B, Ren R
Cell death & disease 2021 Jan 9;12(1):54
Cell death & disease 2021 Jan 9;12(1):54
Lipolytic gene DAGLA is targeted by miR-223 in chicken hepatocytes.
Wang X, Li Y, Qu L, Guo J, Dou T, Hu Y, Ma M, Wang K
Gene 2021 Jan 30;767:145184
Gene 2021 Jan 30;767:145184
Maternal vitamin A deficiency impairs cholinergic and nitrergic neurons, leading to gastrointestinal dysfunction in rat offspring via RARβ.
Tan M, Yang T, Liu H, Xiao L, Li C, Zhu J, Chen J, Li T
Life sciences 2021 Jan 1;264:118688
Life sciences 2021 Jan 1;264:118688
Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model.
Smeltzer S, Quadri Z, Miller A, Zamudio F, Hunter J, Stewart NJF, Saji S, Lee DC, Chaput D, Selenica MB
Biochimica et biophysica acta. Molecular basis of disease 2021 Jan 1;1867(1):165939
Biochimica et biophysica acta. Molecular basis of disease 2021 Jan 1;1867(1):165939
Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer.
Zheng W, Hu J, Lv Y, Bai B, Shan L, Chen K, Dai S, Zhu H
Medical oncology (Northwood, London, England) 2021 Feb 8;38(2):21
Medical oncology (Northwood, London, England) 2021 Feb 8;38(2):21
Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof.
Davis RR, Li B, Yun SY, Chan A, Nareddy P, Gunawan S, Ayaz M, Lawrence HR, Reuther GW, Lawrence NJ, Schönbrunn E
Journal of medicinal chemistry 2021 Feb 25;64(4):2228-2241
Journal of medicinal chemistry 2021 Feb 25;64(4):2228-2241
Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors.
Zhang Y, Wang S, Wu Y, Hou W, Yuan L, Shen C, Wang J, Ye J, Zheng Q, Ma J, Xu J, Wei M, Li Z, Nian S, Xiong H, Zhang L, Shi Y, Fu B, Cao J, Yang C, Li Z, Yang T, Liu L, Yu H, Hu J, Ge S, Chen Y, Zhang T, Zhang J, Cheng T, Yuan Q, Xia N
Small methods 2021 Feb 15;5(2):2001031
Small methods 2021 Feb 15;5(2):2001031
Pretreatment with a glutamine synthetase inhibitor MSO delays the onset of initial seizures induced by pilocarpine in juvenile rats.
Pawlik MJ, Obara-Michlewska M, Popek MP, Czarnecka AM, Czuczwar SJ, Łuszczki J, Kołodziej M, Acewicz A, Wierzba-Bobrowicz T, Albrecht J
Brain research 2021 Feb 15;1753:147253
Brain research 2021 Feb 15;1753:147253
Halofuginone triggers a transcriptional program centered on ribosome biogenesis and function in honey bees.
Flores ME, McNamara-Bordewick NK, Lovinger NL, Snow JW
Insect biochemistry and molecular biology 2021 Dec;139:103667
Insect biochemistry and molecular biology 2021 Dec;139:103667
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600
Bioengineered 2021 Dec;12(1):589-600
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Wu Y, Qi Y, Qiu Z, Chen W
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Ciclesonide activates glucocorticoid signaling in neonatal rat lung but does not trigger adverse effects in the cortex and cerebellum.
Jaumotte JD, Franks AL, Bargerstock EM, Kisanga EP, Menden HL, Ghersi A, Omar M, Wang L, Rudine A, Short KL, Silswal N, Cole TJ, Sampath V, Monaghan-Nichols AP, DeFranco DB
Neurobiology of disease 2021 Aug;156:105422
Neurobiology of disease 2021 Aug;156:105422
Transcriptomic analysis of tumor tissues and organoids reveals the crucial genes regulating the proliferation of lung adenocarcinoma.
Ma X, Yang S, Jiang H, Wang Y, Xiang Z
Journal of translational medicine 2021 Aug 26;19(1):368
Journal of translational medicine 2021 Aug 26;19(1):368
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Zhao Y, He L, Wang T, Zhu L, Yan N
Metabolites 2021 Aug 23;11(8)
Metabolites 2021 Aug 23;11(8)
HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity.
Chai Q, Li S, Collins MK, Li R, Ahmad I, Johnson SF, Frabutt DA, Yang Z, Shen X, Sun L, Hu J, Hultquist JF, Peterlin BM, Zheng YH
Cell reports 2021 Aug 10;36(6):109514
Cell reports 2021 Aug 10;36(6):109514
Pretreatment with LCK inhibitors chemosensitizes cisplatin-resistant endometrioid ovarian tumors.
Crean-Tate KK, Braley C, Dey G, Esakov E, Saygin C, Trestan A, Silver DJ, Turaga SM, Connor EV, DeBernardo R, Michener CM, Rose PG, Lathia J, Reizes O
Journal of ovarian research 2021 Apr 22;14(1):55
Journal of ovarian research 2021 Apr 22;14(1):55
SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer.
Wang X, Zhang H, Sapio R, Yang J, Wong J, Zhang X, Guo JY, Pine S, Van Remmen H, Li H, White E, Liu C, Kiledjian M, Pestov DG, Steven Zheng XF
Nature communications 2021 Apr 15;12(1):2259
Nature communications 2021 Apr 15;12(1):2259
The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma.
Lipchick BC, Utley A, Han Z, Moparthy S, Yun DH, Bianchi-Smiraglia A, Wolff DW, Fink E, Liu L, Furdui CM, Lee J, Lee KP, Nikiforov MA
Blood advances 2021 Apr 13;5(7):1933-1946
Blood advances 2021 Apr 13;5(7):1933-1946
miR-3 Encoded by Hepatitis B Virus Downregulates PTEN Protein Expression and Promotes Cell Proliferation.
Tang J, Xiao X, Jiang Y, Tian Y, Peng Z, Yang M, Xu Z, Gong G
Journal of hepatocellular carcinoma 2020;7:257-269
Journal of hepatocellular carcinoma 2020;7:257-269
Electric field down-regulates CD9 to promote keratinocytes migration through AMPK pathway.
Ji R, Teng M, Zhang Z, Wang W, Zhang Q, Lv Y, Zhang J, Jiang X
International journal of medical sciences 2020;17(7):865-873
International journal of medical sciences 2020;17(7):865-873
LRG1 promotes corneal angiogenesis and lymphangiogenesis in a corneal alkali burn mouse model.
Song S, Cheng J, Yu BJ, Zhou L, Xu HF, Yang LL
International journal of ophthalmology 2020;13(3):365-373
International journal of ophthalmology 2020;13(3):365-373
Recombinant Dual-target MDM2/MDMX Inhibitor Reverses Doxorubicin Resistance through Activation of the TAB1/TAK1/p38 MAPK Pathway in Wild-type p53 Multidrug-resistant Breast Cancer Cells.
Fan Y, Ma K, Jing J, Wang C, Hu Y, Shi Y, Li E, Geng Q
Journal of Cancer 2020;11(1):25-40
Journal of Cancer 2020;11(1):25-40
Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model.
Gu T, Zhao S, Jin G, Song M, Zhi Y, Zhao R, Ma F, Zheng Y, Wang K, Liu H, Xin M, Han W, Li X, Dong CD, Liu K, Dong Z
Frontiers in immunology 2020;11:621441
Frontiers in immunology 2020;11:621441
Salidroside Attenuates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice and Modulates Inflammation of the Gut-Brain Axis.
Xie Z, Lu H, Yang S, Zeng Y, Li W, Wang L, Luo G, Fang F, Zeng T, Cheng W
Frontiers in pharmacology 2020;11:568423
Frontiers in pharmacology 2020;11:568423
Total Glycosides of Cistanche deserticola Promote Neurological Function Recovery by Inducing Neurovascular Regeneration via Nrf-2/Keap-1 Pathway in MCAO/R Rats.
Wang F, Li R, Tu P, Chen J, Zeng K, Jiang Y
Frontiers in pharmacology 2020;11:236
Frontiers in pharmacology 2020;11:236
Ubiquitin C-Terminal Hydrolase L5 (UCHL5) Accelerates the Growth of Endometrial Cancer via Activating the Wnt/β-Catenin Signaling Pathway.
Liu D, Song Z, Wang X, Ouyang L
Frontiers in oncology 2020;10:865
Frontiers in oncology 2020;10:865
Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria.
Ren YZ, Zhang BZ, Zhao XJ, Zhang ZY
Journal of neurochemistry 2020 Sep;154(5):530-546
Journal of neurochemistry 2020 Sep;154(5):530-546
Oral Administration of Geranylgeraniol Rescues Denervation-induced Muscle Atrophy via Suppression of Atrogin-1.
Miyawaki A, Rojasawasthien T, Hitomi S, Aoki Y, Urata M, Inoue A, Matsubara T, Morikawa K, Habu M, Tominaga K, Kokabu S
In vivo (Athens, Greece) 2020 Sep-Oct;34(5):2345-2351
In vivo (Athens, Greece) 2020 Sep-Oct;34(5):2345-2351
FAM122A Inhibits Erythroid Differentiation through GATA1.
Chen J, Zhou Q, Liu MH, Yang YS, Wang YQ, Huang Y, Chen GQ
Stem cell reports 2020 Sep 8;15(3):721-734
Stem cell reports 2020 Sep 8;15(3):721-734
Non-canonical Fzd7 signaling contributes to breast cancer mesenchymal-like stemness involving Col6a1.
Yin P, Bai Y, Wang Z, Sun Y, Gao J, Na L, Zhang Z, Wang W, Zhao C
Cell communication and signaling : CCS 2020 Sep 7;18(1):143
Cell communication and signaling : CCS 2020 Sep 7;18(1):143
RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A.
Chen DB, Xie XW, Zhao YJ, Wang XY, Liao WJ, Chen P, Deng KJ, Fei R, Qin WY, Wang JH, Wu X, Shao QX, Wei L, Chen HS
Scientific reports 2020 Sep 3;10(1):14538
Scientific reports 2020 Sep 3;10(1):14538
CLPTM1L induces estrogen receptor β signaling-mediated radioresistance in non-small cell lung cancer cells.
Li H, Che J, Jiang M, Cui M, Feng G, Dong J, Zhang S, Lu L, Liu W, Fan S
Cell communication and signaling : CCS 2020 Sep 17;18(1):152
Cell communication and signaling : CCS 2020 Sep 17;18(1):152
High salt diet may promote progression of breast tumor through eliciting immune response.
Chen J, Liu X, Huang H, Zhang F, Lu Y, Hu H
International immunopharmacology 2020 Oct;87:106816
International immunopharmacology 2020 Oct;87:106816
Effect of Porphyromonas gingivalis infection on gut dysbiosis and resultant arthritis exacerbation in mouse model.
Hamamoto Y, Ouhara K, Munenaga S, Shoji M, Ozawa T, Hisatsune J, Kado I, Kajiya M, Matsuda S, Kawai T, Mizuno N, Fujita T, Hirata S, Tanimoto K, Nakayama K, Kishi H, Sugiyama E, Kurihara H
Arthritis research & therapy 2020 Oct 19;22(1):249
Arthritis research & therapy 2020 Oct 19;22(1):249
Physiology and Morphological Correlates of Excitatory Transmission are Preserved in Glutamine Transporter SN1-Depleted Mouse Frontal Cortex.
Popek M, Bobula B, Sowa J, Hess G, Frontczak-Baniewicz M, Albrecht J, Zielińska M
Neuroscience 2020 Oct 15;446:124-136
Neuroscience 2020 Oct 15;446:124-136
m(6) A RNA methyltransferases METTL3/14 regulate immune responses to anti-PD-1 therapy.
Wang L, Hui H, Agrawal K, Kang Y, Li N, Tang R, Yuan J, Rana TM
The EMBO journal 2020 Oct 15;39(20):e104514
The EMBO journal 2020 Oct 15;39(20):e104514
AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5.
Zhao W, Shi CS, Harrison K, Hwang IY, Nabar NR, Wang M, Kehrl JH
Journal of immunology (Baltimore, Md. : 1950) 2020 Oct 15;205(8):2255-2264
Journal of immunology (Baltimore, Md. : 1950) 2020 Oct 15;205(8):2255-2264
Daily Oral Administration of Protease-Treated Royal Jelly Protects Against Denervation-Induced Skeletal Muscle Atrophy.
Shirakawa T, Miyawaki A, Matsubara T, Okumura N, Okamoto H, Nakai N, Rojasawasthien T, Morikawa K, Inoue A, Goto A, Washio A, Tsujisawa T, Kawamoto T, Kokabu S
Nutrients 2020 Oct 11;12(10)
Nutrients 2020 Oct 11;12(10)
Endoplasmic Reticulum Stress Affects Cholesterol Homeostasis by Inhibiting LXRα Expression in Hepatocytes and Macrophages.
Wang T, Zhao Y, You Z, Li X, Xiong M, Li H, Yan N
Nutrients 2020 Oct 11;12(10)
Nutrients 2020 Oct 11;12(10)
The beneficial effect of oyster peptides and oyster powder on cyclophosphamide-induced reproductive impairment in male rats: A comparative study.
Li M, Zhou M, Wei Y, Jia F, Yan Y, Zhang R, Cai M, Gu R
Journal of food biochemistry 2020 Nov;44(11):e13468
Journal of food biochemistry 2020 Nov;44(11):e13468
Suppressor of Ty 16 promotes lung cancer malignancy and is negatively regulated by miR-1227-5p.
Yang L, Wang X, Jiao X, Tian B, Zhang M, Zhou C, Wang R, Chen H, Wang B, Li J, Liu J, Zhang G, Liu P
Cancer science 2020 Nov;111(11):4075-4087
Cancer science 2020 Nov;111(11):4075-4087
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.
Prager BC, Vasudevan HN, Dixit D, Bernatchez JA, Wu Q, Wallace LC, Bhargava S, Lee D, King BH, Morton AR, Gimple RC, Pekmezci M, Zhu Z, Siqueira-Neto JL, Wang X, Xie Q, Chen C, Barnett GH, Vogelbaum MA, Mack SC, Chavez L, Perry A, Raleigh DR, Rich JN
Cancer discovery 2020 Nov;10(11):1722-1741
Cancer discovery 2020 Nov;10(11):1722-1741
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation.
Li L, Zhu S, Shu W, Guo Y, Guan Y, Zeng J, Wang H, Han L, Zhang J, Liu X, Li C, Hou X, Gao M, Ge J, Ren C, Zhang H, Schedl T, Guo X, Chen M, Wang Q
Molecular cell 2020 Nov 5;80(3):525-540.e9
Molecular cell 2020 Nov 5;80(3):525-540.e9
LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer.
Shi Q, Li Y, Li S, Jin L, Lai H, Wu Y, Cai Z, Zhu M, Li Q, Li Y, Wang J, Liu Y, Wu Z, Song E, Liu Q
Nature communications 2020 Nov 2;11(1):5513
Nature communications 2020 Nov 2;11(1):5513
Knockout of mouse receptor accessory protein 6 leads to sperm function and morphology defects†.
Devlin DJ, Agrawal Zaneveld S, Nozawa K, Han X, Moye AR, Liang Q, Harnish JM, Matzuk MM, Chen R
Biology of reproduction 2020 May 26;102(6):1234-1247
Biology of reproduction 2020 May 26;102(6):1234-1247
Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OA.
Dai H, Chen R, Gui C, Tao T, Ge Y, Zhao X, Qin R, Yao W, Gu S, Jiang Y, Gui J
Stem cell research & therapy 2020 May 25;11(1):199
Stem cell research & therapy 2020 May 25;11(1):199
Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase.
Wu X, Spence JS, Das T, Yuan X, Chen C, Zhang Y, Li Y, Sun Y, Chandran K, Hang HC, Peng T
Cell chemical biology 2020 May 21;27(5):571-585.e6
Cell chemical biology 2020 May 21;27(5):571-585.e6
Knockout of MMP3 Weakens Solid Tumor Organoids and Cancer Extracellular Vesicles.
Taha EA, Sogawa C, Okusha Y, Kawai H, Oo MW, Elseoudi A, Lu Y, Nagatsuka H, Kubota S, Satoh A, Okamoto K, Eguchi T
Cancers 2020 May 16;12(5)
Cancers 2020 May 16;12(5)
SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP.
Davenne T, Klintman J, Sharma S, Rigby RE, Blest HTW, Cursi C, Bridgeman A, Dadonaite B, De Keersmaecker K, Hillmen P, Chabes A, Schuh A, Rehwinkel J
Cell reports 2020 May 12;31(6):107640
Cell reports 2020 May 12;31(6):107640
Exon 9-deleted CETP inhibits full length-CETP synthesis and promotes cellular triglyceride storage.
Izem L, Liu Y, Morton RE
Journal of lipid research 2020 Mar;61(3):422-431
Journal of lipid research 2020 Mar;61(3):422-431
HJC0152 suppresses human non-small-cell lung cancer by inhibiting STAT3 and modulating metabolism.
Lu L, Li H, Wu X, Rao J, Zhou J, Fan S, Shen Q
Cell proliferation 2020 Mar;53(3):e12777
Cell proliferation 2020 Mar;53(3):e12777
Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ.
Zhang ZH, He JQ, Zhao YY, Chen HC, Tan NH
Acta pharmacologica Sinica 2020 Mar;41(3):373-382
Acta pharmacologica Sinica 2020 Mar;41(3):373-382
Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery.
Dhawan K, Naslavsky N, Caplan S
The Journal of biological chemistry 2020 Mar 20;295(12):3837-3850
The Journal of biological chemistry 2020 Mar 20;295(12):3837-3850
Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade.
Lin X, Dinglin X, Cao S, Zheng S, Wu C, Chen W, Li Q, Hu Q, Zheng F, Wu Z, Lin DC, Yao Y, Xu X, Xie Z, Liu Q, Yao H, Hu H
Cell reports 2020 Jun 9;31(10):107753
Cell reports 2020 Jun 9;31(10):107753
miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells.
Monteleone NJ, Lutz CS
Oncotarget 2020 Jun 30;11(26):2464-2483
Oncotarget 2020 Jun 30;11(26):2464-2483
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25.
Yang L, Liu Q, Zhang X, Liu X, Zhou B, Chen J, Huang D, Li J, Li H, Chen F, Liu J, Xing Y, Chen X, Su S, Song E
Nature 2020 Jul;583(7814):133-138
Nature 2020 Jul;583(7814):133-138
Curcumin promotes osteogenic differentiation of periodontal ligament stem cells through the PI3K/AKT/Nrf2 signaling pathway.
Xiong Y, Zhao B, Zhang W, Jia L, Zhang Y, Xu X
Iranian journal of basic medical sciences 2020 Jul;23(7):954-960
Iranian journal of basic medical sciences 2020 Jul;23(7):954-960
HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.
Hock DH, Reljic B, Ang CS, Muellner-Wong L, Mountford HS, Compton AG, Ryan MT, Thorburn DR, Stroud DA
Molecular & cellular proteomics : MCP 2020 Jul;19(7):1145-1160
Molecular & cellular proteomics : MCP 2020 Jul;19(7):1145-1160
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Wu Y, Zhao Y, He X, He Z, Wang T, Wan L, Chen L, Yan N
Molecular medicine reports 2020 Jan;21(1):249-257
Molecular medicine reports 2020 Jan;21(1):249-257
Cathepsin L interacts with CDK2-AP1 as a potential predictor of prognosis in patients with breast cancer.
Wang Z, Xiang Z, Zhu T, Chen J, Zhong MZ, Huang J, Wang KS, Li L, Sun LQ, Zhou WB
Oncology letters 2020 Jan;19(1):167-176
Oncology letters 2020 Jan;19(1):167-176
Metformin promotes osteogenic differentiation and protects against oxidative stress-induced damage in periodontal ligament stem cells via activation of the Akt/Nrf2 signaling pathway.
Jia L, Xiong Y, Zhang W, Ma X, Xu X
Experimental cell research 2020 Jan 15;386(2):111717
Experimental cell research 2020 Jan 15;386(2):111717
Glibenclamide ameliorates transplant-induced arteriosclerosis and inhibits macrophage migration and MCP-1 expression.
Zou Y, Zhou C, Xu H, Yu J, Ye P, Zhang H, Chen S, Zhao J, Le S, Cui J, Jiang L, Wu J, Xia J
Life sciences 2020 Jan 15;241:117141
Life sciences 2020 Jan 15;241:117141
Calcium Channel α2δ1 Subunit Mediates Secondary Orofacial Hyperalgesia Through PKC-TRPA1/Gap Junction Signaling.
Cui WQ, Chu YX, Xu F, Chen T, Gao L, Feng Y, Hu XM, Yang W, Du LX, Zhang WW, Mao-Ying QL, Mi WL, Wang YQ
The journal of pain 2020 Jan - Feb;21(1-2):238-257
The journal of pain 2020 Jan - Feb;21(1-2):238-257
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, Chang X, Jin Z, Li J, Zhu Z, Liu B, Su L
Oncogene 2020 Feb;39(7):1414-1428
Oncogene 2020 Feb;39(7):1414-1428
Adenosine A2A receptor activation prevents DOCA-salt induced hypertensive cardiac remodeling via iBAT.
Zhou YP, Ruan CC, Kong LR, Gao PJ
Biochemical and biophysical research communications 2020 Feb 19;
Biochemical and biophysical research communications 2020 Feb 19;
Apigenin attenuates pulmonary hypertension by inducing mitochondria-dependent apoptosis of PASMCs via inhibiting the hypoxia inducible factor 1α-KV1.5 channel pathway.
He Y, Fang X, Shi J, Li X, Xie M, Liu X
Chemico-biological interactions 2020 Feb 1;317:108942
Chemico-biological interactions 2020 Feb 1;317:108942
Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
Skowrońska K, Kozłowska H, Albrecht J
Cell calcium 2020 Dec;92:102304
Cell calcium 2020 Dec;92:102304
Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model.
Gao M, Lu W, Shu Y, Yang Z, Sun S, Xu J, Gan S, Zhu S, Qiu G, Zhuo F, Xu S, Wang Y, Chen J, Wu X, Huang J
CNS neuroscience & therapeutics 2020 Dec;26(12):1288-1302
CNS neuroscience & therapeutics 2020 Dec;26(12):1288-1302
Asparagine endopeptidase inhibitor protects against fenpropathrin-induced neurodegeneration via suppressing α-synuclein aggregation and neuroinflammation.
Yu T, Wan F, Liu C, Zhang X, Liu Z, Zhang J, Xiong J, Wang T, Zhang Z
European journal of pharmacology 2020 Dec 5;888:173586
European journal of pharmacology 2020 Dec 5;888:173586
Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail.
Yuan F, Miao Z, Chen W, Wu F, Wei C, Yong J, Xiao C
Journal of biochemistry 2020 Dec 26;168(6):651-657
Journal of biochemistry 2020 Dec 26;168(6):651-657
PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS-driven cancer cells.
Huang Z, Liu M, Li D, Tan Y, Zhang R, Xia Z, Wang P, Jiao B, Liu P, Ren R
The Journal of biological chemistry 2020 Dec 25;295(52):18343-18354
The Journal of biological chemistry 2020 Dec 25;295(52):18343-18354
miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells.
Monteleone NJ, Lutz CS
Oncotarget 2020 Dec 22;11(51):4699-4721
Oncotarget 2020 Dec 22;11(51):4699-4721
Protocol for Site-Specific Photo-Crosslinking Proteomics to Identify Protein-Protein Interactions in Mammalian Cells.
Chen C, Peng T
STAR protocols 2020 Dec 18;1(3):100109
STAR protocols 2020 Dec 18;1(3):100109
PPARγ Deacetylation Confers the Antiatherogenic Effect and Improves Endothelial Function in Diabetes Treatment.
Liu L, Fan L, Chan M, Kraakman MJ, Yang J, Fan Y, Aaron N, Wan Q, Carrillo-Sepulveda MA, Tall AR, Tabas I, Accili D, Qiang L
Diabetes 2020 Aug;69(8):1793-1803
Diabetes 2020 Aug;69(8):1793-1803
Inhibition of USP15 Prevent Glutamate-Induced Oxidative Damage by Activating Nrf2/HO-1 Signaling Pathway in HT22 Cells.
Chen X, Bao G, Liu F
Cellular and molecular neurobiology 2020 Aug;40(6):999-1010
Cellular and molecular neurobiology 2020 Aug;40(6):999-1010
TNF‑α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR‑335‑5p.
Li S, Yin Y, Yao L, Lin Z, Sun S, Zhang J, Li X
Molecular medicine reports 2020 Aug;22(2):1017-1025
Molecular medicine reports 2020 Aug;22(2):1017-1025
Downregulation of GPR183 on infection restricts the early infection and intracellular replication of mycobacterium tuberculosis in macrophage.
Tang J, Shi Y, Zhan L, Qin C
Microbial pathogenesis 2020 Aug;145:104234
Microbial pathogenesis 2020 Aug;145:104234
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Morgan SE, Schroten H, Ishikawa H, Zhao N
Brain sciences 2020 Aug 8;10(8)
Brain sciences 2020 Aug 8;10(8)
Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression.
Chen Z, Liu L, Liu Y, Wang S, Zhang S, Dong R, Xu M, Ma Y, Wang J, Zhang Q, Wei P
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
Experimental and therapeutic medicine 2020 Apr;19(4):2989-2996
STING expression in monocyte-derived macrophages is associated with the progression of liver inflammation and fibrosis in patients with nonalcoholic fatty liver disease.
Wang X, Rao H, Zhao J, Wee A, Li X, Fei R, Huang R, Wu C, Liu F, Wei L
Laboratory investigation; a journal of technical methods and pathology 2020 Apr;100(4):542-552
Laboratory investigation; a journal of technical methods and pathology 2020 Apr;100(4):542-552
Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer.
Okusha Y, Eguchi T, Tran MT, Sogawa C, Yoshida K, Itagaki M, Taha EA, Ono K, Aoyama E, Okamura H, Kozaki KI, Calderwood SK, Takigawa M, Okamoto K
Cancers 2020 Apr 4;12(4)
Cancers 2020 Apr 4;12(4)
EphB4/ TNFR2/ERK/MAPK signaling pathway comprises a signaling axis to mediate the positive effect of TNF-α on osteogenic differentiation.
Zhang Y, Yang C, Ge S, Wang L, Zhang J, Yang P
BMC molecular and cell biology 2020 Apr 16;21(1):29
BMC molecular and cell biology 2020 Apr 16;21(1):29
4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species.
Tian F, Wang Z, He J, Zhang Z, Tan N
European journal of pharmacology 2020 Apr 15;873:172989
European journal of pharmacology 2020 Apr 15;873:172989
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
You S, Liu S, Dong X, Li H, Zhu Y, Hu L
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.
Shi S, Montalbetti N, Wang X, Rush BM, Marciszyn AL, Baty CJ, Tan RJ, Carattino MD, Kleyman TR
The Journal of biological chemistry 2020 Apr 10;295(15):4950-4962
The Journal of biological chemistry 2020 Apr 10;295(15):4950-4962
X-linked inhibitor of apoptosis protein accelerates migration by inducing epithelial-mesenchymal transition through TGF-β signaling pathway in esophageal cancer cells.
Jin Y, Lu X, Wang M, Zhao X, Xue L
Cell & bioscience 2019;9:76
Cell & bioscience 2019;9:76
Roles for IFT172 and Primary Cilia in Cell Migration, Cell Division, and Neocortex Development.
Pruski M, Hu L, Yang C, Wang Y, Zhang JB, Zhang L, Huang Y, Rajnicek AM, St Clair D, McCaig CD, Lang B, Ding YQ
Frontiers in cell and developmental biology 2019;7:287
Frontiers in cell and developmental biology 2019;7:287
Bcl-2 regulates pyroptosis and necroptosis by targeting BH3-like domains in GSDMD and MLKL.
Shi CS, Kehrl JH
Cell death discovery 2019;5:151
Cell death discovery 2019;5:151
SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes.
Shi CS, Nabar NR, Huang NN, Kehrl JH
Cell death discovery 2019;5:101
Cell death discovery 2019;5:101
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
Fan Y, Li M, Ma K, Hu Y, Jing J, Shi Y, Li E, Dong D
Cancer biology & therapy 2019;20(5):617-632
Cancer biology & therapy 2019;20(5):617-632
Pre-existing H4K16ac levels in euchromatin drive DNA repair by homologous recombination in S-phase.
Horikoshi N, Sharma D, Leonard F, Pandita RK, Charaka VK, Hambarde S, Horikoshi NT, Gaur Khaitan P, Chakraborty S, Cote J, Godin B, Hunt CR, Pandita TK
Communications biology 2019;2:253
Communications biology 2019;2:253
CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17.
Liu J, Zhu G, Jia N, Wang W, Wang Y, Yin M, Jiang X, Huang Y, Zhang J
International journal of biological sciences 2019;15(2):493-506
International journal of biological sciences 2019;15(2):493-506
Long Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21.
Lyu K, Xu Y, Yue H, Li Y, Zhao J, Chen L, Wu J, Zhu X, Chai L, Li C, Wen W, Lei W
Cancer management and research 2019;11:8487-8498
Cancer management and research 2019;11:8487-8498
Ten-Eleven Translocation (TET) Enzymes Modulate the Activation of Dendritic Cells in Allergic Rhinitis.
Li H, Lu T, Sun W, Ma R, Zhong H, Wei Y, Chen D, Wen Y, Carlsten C, Wen W
Frontiers in immunology 2019;10:2271
Frontiers in immunology 2019;10:2271
Suhuang Antitussive Capsules-Ameliorative Effects on LPS-Induced Sputum Obstruction in Mice Through Promoting HGF Secretion.
Tong X, Liang R, Jia Y, Qin W, Guo C, Wu X, Wang Z, Chen D, Tan N
Frontiers in pharmacology 2019;10:1422
Frontiers in pharmacology 2019;10:1422
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death.
Bosnakovski D, da Silva MT, Sunny ST, Ener ET, Toso EA, Yuan C, Cui Z, Walters MA, Jadhav A, Kyba M
Science advances 2019 Sep;5(9):eaaw7781
Science advances 2019 Sep;5(9):eaaw7781
Nicotinic acetylcholine receptor subunit expression in the gastrocnemius and in the orbicularis oris before and after facial nerve injury in rats.
Xu J, Huang Y, Li S, Chen L, Xue Z
Neurological research 2019 Sep;41(9):817-826
Neurological research 2019 Sep;41(9):817-826
Different signalling in infarcted and non-infarcted areas of rat failing hearts: A role of necroptosis and inflammation.
Lichý M, Szobi A, Hrdlička J, Horváth C, Kormanová V, Rajtík T, Neckář J, Kolář F, Adameová A
Journal of cellular and molecular medicine 2019 Sep;23(9):6429-6441
Journal of cellular and molecular medicine 2019 Sep;23(9):6429-6441
Potential roles of lncRNA-Cox2 and EGR1 in regulating epidural fibrosis following laminectomy.
Qian ZY, Jiang F, Tang J, Ge DW, Chen HT, Zheng SN, Cao XJ, Ge YB, Yang L
European review for medical and pharmacological sciences 2019 Sep;23(17):7191-7199
European review for medical and pharmacological sciences 2019 Sep;23(17):7191-7199
Regulation of the Metal Transporters ZIP14 and ZnT10 by Manganese Intake in Mice.
Felber DM, Wu Y, Zhao N
Nutrients 2019 Sep 4;11(9)
Nutrients 2019 Sep 4;11(9)
Simvastatin promotes endothelial dysfunction by activating the Wnt/β‑catenin pathway under oxidative stress.
He Z, Du X, Wu Y, Hua L, Wan L, Yan N
International journal of molecular medicine 2019 Oct;44(4):1289-1298
International journal of molecular medicine 2019 Oct;44(4):1289-1298
Tissue-Resident Macrophages Promote Renal Cystic Disease.
Zimmerman KA, Song CJ, Li Z, Lever JM, Crossman DK, Rains A, Aloria EJ, Gonzalez NM, Bassler JR, Zhou J, Crowley MR, Revell DZ, Yan Z, Shan D, Benveniste EN, George JF, Mrug M, Yoder BK
Journal of the American Society of Nephrology : JASN 2019 Oct;30(10):1841-1856
Journal of the American Society of Nephrology : JASN 2019 Oct;30(10):1841-1856
Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma.
Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, Wang Z, Tan N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109188
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109188
Increased miRNA-518b inhibits trophoblast migration and angiogenesis by targeting EGR1 in early embryonic arrest†.
Yang W, Lu Z, Zhi Z, Liu L, Deng L, Jiang X, Pang L
Biology of reproduction 2019 Oct 25;101(4):664-674
Biology of reproduction 2019 Oct 25;101(4):664-674
Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer.
Hu XM, Yang W, Du LX, Cui WQ, Mi WL, Mao-Ying QL, Chu YX, Wang YQ
Anesthesiology 2019 Nov;131(5):1125-1147
Anesthesiology 2019 Nov;131(5):1125-1147
Analyses of epithelial Na+ channel variants reveal that an extracellular β-ball domain critically regulates ENaC gating.
Wang X, Chen J, Shi S, Sheng S, Kleyman TR
The Journal of biological chemistry 2019 Nov 8;294(45):16765-16775
The Journal of biological chemistry 2019 Nov 8;294(45):16765-16775
Study of chromatin remodeling genes implicates SMARCA4 as a putative player in oncogenesis in neuroblastoma.
Bellini A, Bessoltane-Bentahar N, Bhalshankar J, Clement N, Raynal V, Baulande S, Bernard V, Danzon A, Chicard M, Colmet-Daage L, Pierron G, Le Roux L, Planchon JM, Combaret V, Lapouble E, Corradini N, Thebaud E, Gambart M, Valteau-Couanet D, Michon J, Louis-Brennetot C, Janoueix-Lerosey I, Defachelles AS, Bourdeaut F, Delattre O, Schleiermacher G
International journal of cancer 2019 Nov 15;145(10):2781-2791
International journal of cancer 2019 Nov 15;145(10):2781-2791
MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium.
Xie S, Farmer T, Naslavsky N, Caplan S
Journal of cell science 2019 Nov 14;132(22)
Journal of cell science 2019 Nov 14;132(22)
The mTOR-RUNX1 pathway regulates DC-SIGN expression in renal tubular epithelial cells.
Zhou S, Zhang L, Feng D, Luo M, Xie R, Yang K, Xu D, Yang K, Fei J, Zhou T
Biochemical and biophysical research communications 2019 Nov 12;519(3):620-625
Biochemical and biophysical research communications 2019 Nov 12;519(3):620-625
Involvement of autophagy in hypoxia-BNIP3 signaling to promote epidermal keratinocyte migration.
Zhang J, Zhang C, Jiang X, Li L, Zhang D, Tang D, Yan T, Zhang Q, Yuan H, Jia J, Hu J, Zhang J, Huang Y
Cell death & disease 2019 Mar 8;10(3):234
Cell death & disease 2019 Mar 8;10(3):234
CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.
Liu J, Zhang X, Chen K, Cheng Y, Liu S, Xia M, Chen Y, Zhu H, Li Z, Cao X
Immunity 2019 Mar 19;50(3):600-615.e15
Immunity 2019 Mar 19;50(3):600-615.e15
Tumor-Contacted Neutrophils Promote Metastasis by a CD90-TIMP-1 Juxtacrine-Paracrine Loop.
Wang Y, Chen J, Yang L, Li J, Wu W, Huang M, Lin L, Su S
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Mar 15;25(6):1957-1969
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Mar 15;25(6):1957-1969
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Scheiber IF, Wu Y, Morgan SE, Zhao N
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
Programmable RNA-Guided RNA Effector Proteins Built from Human Parts.
Rauch S, He E, Srienc M, Zhou H, Zhang Z, Dickinson BC
Cell 2019 Jun 27;178(1):122-134.e12
Cell 2019 Jun 27;178(1):122-134.e12
Sphingomyelin Synthase 2 Promotes Endothelial Dysfunction by Inducing Endoplasmic Reticulum Stress.
Hua L, Wu N, Zhao R, He X, Liu Q, Li X, He Z, Yu L, Yan N
International journal of molecular sciences 2019 Jun 12;20(12)
International journal of molecular sciences 2019 Jun 12;20(12)
An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis.
Mayank AK, Pandey V, Vashisht AA, Barshop WD, Rayatpisheh S, Sharma T, Haque T, Powers DN, Wohlschlegel JA
Molecular cell 2019 Jul 25;75(2):382-393.e5
Molecular cell 2019 Jul 25;75(2):382-393.e5
Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area.
Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY
Neuron 2019 Jul 17;103(2):309-322.e7
Neuron 2019 Jul 17;103(2):309-322.e7
MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection.
Arifuzzaman M, Mobley YR, Choi HW, Bist P, Salinas CA, Brown ZD, Chen SL, Staats HF, Abraham SN
Science advances 2019 Jan;5(1):eaav0216
Science advances 2019 Jan;5(1):eaav0216
Effect of 1α, 25-dihydroxyvitamin D3 on the osteogenic differentiation of human periodontal ligament stem cells and the underlying regulatory mechanism.
Ji Y, Zhang P, Xing Y, Jia L, Zhang Y, Jia T, Wu X, Zhao B, Xu X
International journal of molecular medicine 2019 Jan;43(1):167-176
International journal of molecular medicine 2019 Jan;43(1):167-176
Persistent Overexposure to N-Methyl-D-Aspartate (NMDA) Calcium-Dependently Downregulates Glutamine Synthetase, Aquaporin 4, and Kir4.1 Channel in Mouse Cortical Astrocytes.
Skowrońska K, Obara-Michlewska M, Czarnecka A, Dąbrowska K, Zielińska M, Albrecht J
Neurotoxicity research 2019 Jan;35(1):271-280
Neurotoxicity research 2019 Jan;35(1):271-280
Spinal Serotonin 1A Receptor Contributes to the Analgesia of Acupoint Catgut Embedding by Inhibiting Phosphorylation of the N-Methyl-d-Aspartate Receptor GluN1 Subunit in Complete Freund's Adjuvant-Induced Inflammatory Pain in Rats.
Cui WQ, Sun WS, Xu F, Hu XM, Yang W, Zhou Y, Du LX, Zhang WW, Mao-Ying QL, Mi WL, Chu YX, Wang YQ
The journal of pain 2019 Jan;20(1):16.e1-16.e16
The journal of pain 2019 Jan;20(1):16.e1-16.e16
Repurposing of mTOR Complex Inhibitors Attenuates MCL-1 and Sensitizes to PARP Inhibition.
Mattoo AR, Joun A, Jessup JM
Molecular cancer research : MCR 2019 Jan;17(1):42-53
Molecular cancer research : MCR 2019 Jan;17(1):42-53
PKP3 interactions with MAPK-JNK-ERK1/2-mTOR pathway regulates autophagy and invasion in ovarian cancer.
Lim V, Zhu H, Diao S, Hu L, Hu J
Biochemical and biophysical research communications 2019 Jan 8;508(2):646-653
Biochemical and biophysical research communications 2019 Jan 8;508(2):646-653
Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway.
Majewska E, Márquez J, Albrecht J, Szeliga M
Cancers 2019 Jan 19;11(1)
Cancers 2019 Jan 19;11(1)
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.
Han D, Liu J, Chen C, Dong L, Liu Y, Chang R, Huang X, Liu Y, Wang J, Dougherty U, Bissonnette MB, Shen B, Weichselbaum RR, Xu MM, He C
Nature 2019 Feb;566(7743):270-274
Nature 2019 Feb;566(7743):270-274
Potential ceRNA networks involved in autophagy suppression of pancreatic cancer caused by chloroquine diphosphate: A study based on differentially‑expressed circRNAs, lncRNAs, miRNAs and mRNAs.
Wei DM, Jiang MT, Lin P, Yang H, Dang YW, Yu Q, Liao DY, Luo DZ, Chen G
International journal of oncology 2019 Feb;54(2):600-626
International journal of oncology 2019 Feb;54(2):600-626
MiR-552 promotes the proliferation, migration and EMT of hepatocellular carcinoma cells by inhibiting AJAP1 expression.
Qu W, Wen X, Su K, Gou W
Journal of cellular and molecular medicine 2019 Feb;23(2):1541-1552
Journal of cellular and molecular medicine 2019 Feb;23(2):1541-1552
Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells.
Liu S, Hou H, Zhang P, Wu Y, He X, Li H, Yan N
Molecular medicine reports 2019 Feb;19(2):1159-1167
Molecular medicine reports 2019 Feb;19(2):1159-1167
Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer.
Yang J, Zhang X, Chen Z, Shen Y, Wang F, Wang Y, Liu Y, Liu P, Yang J
Cell death & disease 2019 Feb 21;10(3):179
Cell death & disease 2019 Feb 21;10(3):179
Murine PAIP1 stimulates translation of spermiogenic mRNAs stored by YBX2 via its interaction with YBX2†.
He Y, Lin Y, Zhu Y, Ping P, Wang G, Sun F
Biology of reproduction 2019 Feb 1;100(2):561-572
Biology of reproduction 2019 Feb 1;100(2):561-572
Rutin promotes the formation and osteogenic differentiation of human periodontal ligament stem cell sheets in vitro.
Zhao B, Zhang Y, Xiong Y, Xu X
International journal of molecular medicine 2019 Dec;44(6):2289-2297
International journal of molecular medicine 2019 Dec;44(6):2289-2297
A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability.
Xia B, Hong T, He X, Hu X, Gao Y
Cell transplantation 2019 Dec;28(12):1614-1623
Cell transplantation 2019 Dec;28(12):1614-1623
Translation of yes-associated protein (YAP) was antagonized by its circular RNA via suppressing the assembly of the translation initiation machinery.
Wu N, Yuan Z, Du KY, Fang L, Lyu J, Zhang C, He A, Eshaghi E, Zeng K, Ma J, Du WW, Yang BB
Cell death and differentiation 2019 Dec;26(12):2758-2773
Cell death and differentiation 2019 Dec;26(12):2758-2773
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Melum E, Jiang X, Baker KD, Macedo MF, Fritsch J, Dowds CM, Wang J, Pharo A, Kaser A, Tan C, Pereira CS, Kelly SL, Duan J, Karlsen TH, Exley MA, Schütze S, Zajonc DM, Merrill AH, Schuchman EH, Zeissig S, Blumberg RS
Nature immunology 2019 Dec;20(12):1644-1655
Nature immunology 2019 Dec;20(12):1644-1655
LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription.
Xiu B, Chi Y, Liu L, Chi W, Zhang Q, Chen J, Guo R, Si J, Li L, Xue J, Shao ZM, Wu ZH, Huang S, Wu J
Molecular cancer 2019 Dec 19;18(1):187
Molecular cancer 2019 Dec 19;18(1):187
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Chong KY, Kang M, Garofalo F, Ueno D, Liang H, Cady S, Madarikan O, Pitruzzello N, Tsai CH, Hartwich TMP, Shuch BM, Yang-Hartwich Y
Molecular pharmacology 2019 Aug;96(2):168-179
Molecular pharmacology 2019 Aug;96(2):168-179
Aggregatibacter actinomycetemcomitans Leukotoxin (LtxA) Requires Death Receptor Fas, in Addition to LFA-1, To Trigger Cell Death in T Lymphocytes.
Vega BA, Schober LT, Kim T, Belinka BA Jr, Kachlany SC
Infection and immunity 2019 Aug;87(8)
Infection and immunity 2019 Aug;87(8)
Palmitoylation is required for TNF-R1 signaling.
Zingler P, Särchen V, Glatter T, Caning L, Saggau C, Kathayat RS, Dickinson BC, Adam D, Schneider-Brachert W, Schütze S, Fritsch J
Cell communication and signaling : CCS 2019 Aug 5;17(1):90
Cell communication and signaling : CCS 2019 Aug 5;17(1):90
PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
Fons NR, Sundaram RK, Breuer GA, Peng S, McLean RL, Kalathil AN, Schmidt MS, Carvalho DM, Mackay A, Jones C, Carcaboso ÁM, Nazarian J, Berens ME, Brenner C, Bindra RS
Nature communications 2019 Aug 22;10(1):3790
Nature communications 2019 Aug 22;10(1):3790
Mutations in topoisomerase IIβ result in a B cell immunodeficiency.
Broderick L, Yost S, Li D, McGeough MD, Booshehri LM, Guaderrama M, Brydges SD, Kucharova K, Patel NC, Harr M, Hakonarson H, Zackai E, Cowell IG, Austin CA, Hügle B, Gebauer C, Zhang J, Xu X, Wang J, Croker BA, Frazer KA, Putnam CD, Hoffman HM
Nature communications 2019 Aug 13;10(1):3644
Nature communications 2019 Aug 13;10(1):3644
CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.
Li K, Meng Z, Jiang L, Xia C, Xu K, Yuan D, Chen H, Zhang B, Liu S
Molecular and cellular probes 2019 Apr;44:57-62
Molecular and cellular probes 2019 Apr;44:57-62
BP‑1‑102 exerts an antitumor effect on the AGS human gastric cancer cell line through modulating the STAT3 and MAPK signaling pathways.
Jiang X, Tang J, Wu M, Chen S, Xu Z, Wang H, Wang H, Yu X, Li Z, Teng L
Molecular medicine reports 2019 Apr;19(4):2698-2706
Molecular medicine reports 2019 Apr;19(4):2698-2706
Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production.
Kotredes KP, Razmpour R, Lutton E, Alfonso-Prieto M, Ramirez SH, Gamero AM
Oncotarget 2019 Apr 12;10(28):2675-2692
Oncotarget 2019 Apr 12;10(28):2675-2692
miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer.
Monteleone NJ, Moore AE, Iacona JR, Lutz CS, Dixon DA
Scientific reports 2019 Apr 1;9(1):5405
Scientific reports 2019 Apr 1;9(1):5405
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
Gou Y, Li X, Li P, Zhang H, Xu T, Wang H, Wang B, Ma X, Jiang X, Zhang Z
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
FEZF1 is an Independent Predictive Factor for Recurrence and Promotes Cell Proliferation and Migration in Cervical Cancer.
Lan Y, Xiao X, Luo Y, He Z, Song X
Journal of Cancer 2018;9(21):3929-3938
Journal of Cancer 2018;9(21):3929-3938
Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer.
Xiang Z, Huang X, Wang J, Zhang J, Ji J, Yan R, Zhu Z, Cai W, Yu Y
Frontiers in pharmacology 2018;9:861
Frontiers in pharmacology 2018;9:861
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
Li X, Qiu Z, Jin Q, Chen G, Guo M
Frontiers in pharmacology 2018;9:629
Frontiers in pharmacology 2018;9:629
Decrease of Perivascular Adipose Tissue Browning Is Associated With Vascular Dysfunction in Spontaneous Hypertensive Rats During Aging.
Kong LR, Zhou YP, Chen DR, Ruan CC, Gao PJ
Frontiers in physiology 2018;9:400
Frontiers in physiology 2018;9:400
Emblic Leafflower (Phyllanthus emblica L.) Fruits Ameliorate Vascular Smooth Muscle Cell Dysfunction in Hyperglycemia: An Underlying Mechanism Involved in Ellagitannin Metabolite Urolithin A.
Zhou J, Zhang C, Zheng GH, Qiu Z
Evidence-based complementary and alternative medicine : eCAM 2018;2018:8478943
Evidence-based complementary and alternative medicine : eCAM 2018;2018:8478943
The downregulation of WWOX induces epithelial-mesenchymal transition and enhances stemness and chemoresistance in breast cancer.
Li J, Liu J, Li P, Zhou C, Liu P
Experimental biology and medicine (Maywood, N.J.) 2018 Sep;243(13):1066-1073
Experimental biology and medicine (Maywood, N.J.) 2018 Sep;243(13):1066-1073
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
Liu J, Eckert MA, Harada BT, Liu SM, Lu Z, Yu K, Tienda SM, Chryplewicz A, Zhu AC, Yang Y, Huang JT, Chen SM, Xu ZG, Leng XH, Yu XC, Cao J, Zhang Z, Liu J, Lengyel E, He C
Nature cell biology 2018 Sep;20(9):1074-1083
Nature cell biology 2018 Sep;20(9):1074-1083
A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21.
Ruan CC, Kong LR, Chen XH, Ma Y, Pan XX, Zhang ZB, Gao PJ
Cell metabolism 2018 Sep 4;28(3):476-489.e5
Cell metabolism 2018 Sep 4;28(3):476-489.e5
Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors.
Lopez Sambrooks C, Baro M, Quijano A, Narayan A, Cui W, Greninger P, Egan R, Patel A, Benes CH, Saltzman WM, Contessa JN
Cancer research 2018 Sep 1;78(17):5094-5106
Cancer research 2018 Sep 1;78(17):5094-5106
The proliferation of colorectal cancer cells is suppressed by silencing of EIF3H.
Yu G, Liao J, Wu J, Ding J, Zhang L
Bioscience, biotechnology, and biochemistry 2018 Oct;82(10):1694-1701
Bioscience, biotechnology, and biochemistry 2018 Oct;82(10):1694-1701
Progranulin Is Positively Associated with Intervertebral Disc Degeneration by Interaction with IL-10 and IL-17 Through TNF Pathways.
Wang S, Wei J, Fan Y, Ding H, Tian H, Zhou X, Cheng L
Inflammation 2018 Oct;41(5):1852-1863
Inflammation 2018 Oct;41(5):1852-1863
Loss of miR-146b-3p Inhibits Perivascular Adipocyte Browning with Cold Exposure During Aging.
Pan XX, Cao JM, Cai F, Ruan CC, Wu F, Gao PJ
Cardiovascular drugs and therapy 2018 Oct;32(5):511-518
Cardiovascular drugs and therapy 2018 Oct;32(5):511-518
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Xia Y, Yu B, Ma C, Tu Y, Zhai L, Yang Y, Liu D, Liu Y, Wu H, Dan H, You P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages.
Su S, Zhao J, Xing Y, Zhang X, Liu J, Ouyang Q, Chen J, Su F, Liu Q, Song E
Cell 2018 Oct 4;175(2):442-457.e23
Cell 2018 Oct 4;175(2):442-457.e23
Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors.
Rinis N, Golden JE, Marceau CD, Carette JE, Van Zandt MC, Gilmore R, Contessa JN
Cell chemical biology 2018 Oct 18;25(10):1231-1241.e4
Cell chemical biology 2018 Oct 18;25(10):1231-1241.e4
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.
Bianchi-Smiraglia A, Bagati A, Fink EE, Affronti HC, Lipchick BC, Moparthy S, Long MD, Rosario SR, Lightman SM, Moparthy K, Wolff DW, Yun DH, Han Z, Polechetti A, Roll MV, Gitlin II, Leonova KI, Rowsam AM, Kandel ES, Gudkov AV, Bergsagel PL, Lee KP, Smiraglia DJ, Nikiforov MA
The Journal of clinical investigation 2018 Oct 1;128(10):4682-4696
The Journal of clinical investigation 2018 Oct 1;128(10):4682-4696
Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning.
Mao M, Hu Y, Yang Y, Qian Y, Wei H, Fan W, Yang Y, Li X, Wang Z
Cell systems 2018 Nov 28;7(5):510-520.e4
Cell systems 2018 Nov 28;7(5):510-520.e4
After Treatment with Methylene Blue is Effective against Delayed Encephalopathy after Acute Carbon Monoxide Poisoning.
Zhao N, Liang P, Zhuo X, Su C, Zong X, Guo B, Han D, Yan X, Hu S, Zhang Q, Tie X
Basic & clinical pharmacology & toxicology 2018 May;122(5):470-480
Basic & clinical pharmacology & toxicology 2018 May;122(5):470-480
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
Papadopoulos N, Lennartsson J, Heldin CH
The Journal of cell biology 2018 May 7;217(5):1701-1717
The Journal of cell biology 2018 May 7;217(5):1701-1717
β1-Integrin Impacts Rad51 Stability and DNA Double-Strand Break Repair by Homologous Recombination.
Ahmed KM, Pandita RK, Singh DK, Hunt CR, Pandita TK
Molecular and cellular biology 2018 May 1;38(9)
Molecular and cellular biology 2018 May 1;38(9)
hsa-miR-212 modulates the radiosensitivity of glioma cells by targeting BRCA1.
He X, Fan S
Oncology reports 2018 Mar;39(3):977-984
Oncology reports 2018 Mar;39(3):977-984
Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer.
Lan Y, Xiao X, He Z, Luo Y, Wu C, Li L, Song X
Nucleic acids research 2018 Jun 20;46(11):5809-5821
Nucleic acids research 2018 Jun 20;46(11):5809-5821
miR-146a suppresses 5-lipoxygenase activating protein (FLAP) expression and Leukotriene B4 production in lung cancer cells.
Iacona JR, Monteleone NJ, Lutz CS
Oncotarget 2018 Jun 1;9(42):26751-26769
Oncotarget 2018 Jun 1;9(42):26751-26769
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.
Hertzog J, Dias Junior AG, Rigby RE, Donald CL, Mayer A, Sezgin E, Song C, Jin B, Hublitz P, Eggeling C, Kohl A, Rehwinkel J
European journal of immunology 2018 Jul;48(7):1120-1136
European journal of immunology 2018 Jul;48(7):1120-1136
Myricetin suppresses breast cancer metastasis through down-regulating the activity of matrix metalloproteinase (MMP)-2/9.
Ci Y, Zhang Y, Liu Y, Lu S, Cao J, Li H, Zhang J, Huang Z, Zhu X, Gao J, Han M
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Phytotherapy research : PTR 2018 Jul;32(7):1373-1381
Elevated CRB3 expression suppresses breast cancer stemness by inhibiting β-catenin signalling to restore tamoxifen sensitivity.
Li P, Feng C, Chen H, Jiang Y, Cao F, Liu J, Liu P
Journal of cellular and molecular medicine 2018 Jul;22(7):3423-3433
Journal of cellular and molecular medicine 2018 Jul;22(7):3423-3433
Differential HDAC6 Activity Modulates Ciliogenesis and Subsequent Mechanosensing of Endothelial Cells Derived from Pluripotent Stem Cells.
Smith Q, Macklin B, Chan XY, Jones H, Trempel M, Yoder MC, Gerecht S
Cell reports 2018 Jul 24;24(4):895-908.e6
Cell reports 2018 Jul 24;24(4):895-908.e6
mfat-1 transgene protects cultured adult neural stem cells against cobalt chloride-mediated hypoxic injury by activating Nrf2/ARE pathways.
Yu J, Yang H, Fang B, Zhang Z, Wang Y, Dai Y
Journal of neuroscience research 2018 Jan;96(1):87-102
Journal of neuroscience research 2018 Jan;96(1):87-102
Morphological and molecular variations induce mitochondrial dysfunction as a possible underlying mechanism of athletic amenorrhea.
Xiong RH, Wen SL, Wang Q, Zhou HY, Feng S
Experimental and therapeutic medicine 2018 Jan;15(1):993-998
Experimental and therapeutic medicine 2018 Jan;15(1):993-998
Tumor necrosis factor-alpha inhibits osteogenic differentiation of pre-osteoblasts by downregulation of EphB4 signaling via activated nuclear factor-kappaB signaling pathway.
Wang LM, Zhao N, Zhang J, Sun QF, Yang CZ, Yang PS
Journal of periodontal research 2018 Feb;53(1):66-72
Journal of periodontal research 2018 Feb;53(1):66-72
CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness.
Su S, Chen J, Yao H, Liu J, Yu S, Lao L, Wang M, Luo M, Xing Y, Chen F, Huang D, Zhao J, Yang L, Liao D, Su F, Li M, Liu Q, Song E
Cell 2018 Feb 8;172(4):841-856.e16
Cell 2018 Feb 8;172(4):841-856.e16
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway.
Zhang P, Hua L, Hou H, Du X, He Z, Liu M, Hu X, Yan N
International journal of molecular medicine 2018 Dec;42(6):3344-3354
International journal of molecular medicine 2018 Dec;42(6):3344-3354
β-actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprograming.
Xie X, Jankauskas R, Mazari AMA, Drou N, Percipalle P
PLoS genetics 2018 Dec;14(12):e1007846
PLoS genetics 2018 Dec;14(12):e1007846
An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo.
Cen B, Wei Y, Huang W, Teng M, He S, Li J, Wang W, He G, Bai X, Liu X, Yuan Y, Pan X, Ji A
Molecular therapy. Nucleic acids 2018 Dec 7;13:220-232
Molecular therapy. Nucleic acids 2018 Dec 7;13:220-232
An In Vitro Comparative Study of Multisource Derived Human Mesenchymal Stem Cells for Bone Tissue Engineering.
Zhang Y, Xing Y, Jia L, Ji Y, Zhao B, Wen Y, Xu X
Stem cells and development 2018 Dec 1;27(23):1634-1645
Stem cells and development 2018 Dec 1;27(23):1634-1645
Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats.
Liu SY, Chen L, Li XC, Hu QK, He LJ
Journal of chemical neuroanatomy 2018 Apr;89:37-42
Journal of chemical neuroanatomy 2018 Apr;89:37-42
High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer.
Chen Y, Liu J, Wang W, Xiang L, Wang J, Liu S, Zhou H, Guo Z
Oncology reports 2018 Apr;39(4):1693-1701
Oncology reports 2018 Apr;39(4):1693-1701
AmotP130 regulates Rho GTPase and decreases breast cancer cell mobility.
Chen ZL, Yang J, Shen YW, Li ST, Wang X, Lv M, Wang BY, Li P, Zhao W, Qiu RY, Liu Y, Liu PJ, Yang J
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Archives of pharmacal research 2014 Aug;37(8):1086-95
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot analysis of GAPDH in various tissues and cell lines using Proteintech antibody HRP-60004 at a dilution of 1:10000.
- Sample type
- tissue