MAB248

antibody from R&D Systems

Targeting: BDNF

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

MAB248

Provider

R&D Systems

Product name

Anti-Human BDNF Monoclonal Antibody (Clone 35928)

Antibody type

Monoclonal

Antigen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human BDNF, Arg128-Arg247

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

P23560


Isotype

IgG

Vial size

500 µg

References

Submitted references

CD44v3+/CD24- cells possess cancer stem cell-like properties in human oral squamous cell carcinoma.

Todoroki K, Ogasawara S, Akiba J, Nakayama M, Naito Y, Seki N, Kusukawa J, Yano H
International journal of oncology 2016 Jan;48(1):99-109

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Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival.

Vanhecke E, Adriaenssens E, Verbeke S, Meignan S, Germain E, Berteaux N, Nurcombe V, Le Bourhis X, Hondermarck H
Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Apr 1;17(7):1741-52

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Decreased BDNF levels are a major contributor to the embryonic phenotype of huntingtin knockdown zebrafish.

Diekmann H, Anichtchik O, Fleming A, Futter M, Goldsmith P, Roach A, Rubinsztein DC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Feb 4;29(5):1343-9

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Brain-derived neurotrophic factor (BDNF) and TrkB in the piglet brainstem after post-natal nicotine and intermittent hypercapnic hypoxia.

Tang S, Machaalani R, Waters KA
Brain research 2008 Sep 26;1232:195-205

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Neurotrophins modulate monocyte chemotaxis without affecting macrophage function.

Samah B, Porcheray F, Gras G
Clinical and experimental immunology 2008 Mar;151(3):476-86

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BDNF and its receptors in human myasthenic thymus: implications for cell fate in thymic pathology.

Berzi A, Ayata CK, Cavalcante P, Falcone C, Candiago E, Motta T, Bernasconi P, Hohlfeld R, Mantegazza R, Meinl E, Farina C
Journal of neuroimmunology 2008 Jul 15;197(2):128-39

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Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis.

Sung SY, Hsieh CL, Law A, Zhau HE, Pathak S, Multani AS, Lim S, Coleman IM, Wu LC, Figg WD, Dahut WL, Nelson P, Lee JK, Amin MB, Lyles R, Johnstone PA, Marshall FF, Chung LW
Cancer research 2008 Dec 1;68(23):9996-10003

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Brain-derived neurotrophic factor mRNA and protein in the piglet brainstem and effects of Intermittent Hypercapnic Hypoxia.

Peiris TS, Machaalani R, Waters KA
Brain research 2004 Dec 10;1029(1):11-23