NB100-65011V

antibody from Novus Biologicals

Targeting: HLA-DRB1 HLA-DR1B

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NB100-65011V

Provider

Novus Biologicals

Product name

Mouse Monoclonal MHC Class II RT1Bu Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. NB100-65011 recognizes a polymorphic determinant of rat Ia antigen (RT1Bu) present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains (1,2). This antibody is useful for distinguishing Ia positive cells from different rat strains, e.g. for recognizing cells of donor origin in bone marrow reconstituted radiation chimaeras (3,4). MRC OX-3 cross reacts with mouse strains of MHC haplotypes b and s, and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. NB100-65011 recognizes Ia antigens on B-cells, dendritic cells and certain epithelial cells (1,3,4). This product is routinely tested in flow cytometry on Lewis rat splenocytes.

Reactivity

Mouse, Rat

Host

Mouse

Conjugate

Blue dye

Isotype

IgG

Vial size

0.25 ml

Storage

Store at 4C in the dark.