PA1-4735

antibody from Invitrogen Antibodies

Targeting: PRKN AR-JP, PARK2, parkin, PDJ

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PA1-4735

Provider

Invitrogen Antibodies

Product name

Phospho-Parkin (Ser378) Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Storage

-20° C, Avoid Freeze/Thaw Cycles

References

Submitted references

Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.

Lonskaya I, Shekoyan AR, Hebron ML, Desforges N, Algarzae NK, Moussa CE
Journal of Alzheimer's disease : JAD 2013;33(1):231-47

Western blot

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Western blot of Phospho-Parkin pSer101 in HEK293 cells transfected with Parkin WT (Phospho) and Parkin Ser378 mutant (non-phospho) using a polyclonal antibody (Product # PA1-4735). Results show the phospho-specific immunolabeling of the ~ 52k Parkin protein and lack of immunolabeling in the Parkin Ser378 mutant.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Western blot of Parkin in HEK293 cells transfected with Parkin wild type and Parkin S378 mutant showing the specific immunolabeling of a band at ~52 kDa corresponding to Phospho-Parkin (Ser378) polyclonal antibody (Product # PA1-4735).