ALAS1

gene product
ALAS, ALAS3
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
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74 antibodies from 14 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
6 antibodies
Abnova Corporation
3 antibodies
Atlas Antibodies
1 antibody
antibodies-online
36 antibodies
Santa Cruz Biotechnology
1 antibody
LifeSpan BioSciences, Inc.
6 antibodies
Acris Antibodies GmbH
2 antibodies
Thermo Fisher Scientific Pierce
2 antibodies
Aviva Systems Biology
2 antibodies
GeneTex
1 antibody
Creative Biomart
7 antibodies
RabMAbs
1 antibody
United States Biological
4 antibodies
Sigma-Aldrich
2 antibodies