TAB-015-F(E)

antibody from Creative Biolabs

Targeting: ITGA2B CD41, CD41B, GP2B, PPP1R93

No application information provided.

Antibody Data

Product number

TAB-015-F(E)

Provider

Creative Biolabs

Product name

Anti-Human CD41 Recombinant Antibody Fab Fragment (Abciximab)

Antibody type

Monoclonal

Description

Recombinant monoclonal antibody Fragment Fab to Human CD41. Abciximab (previously known as c7E3 Fab), a glycoprotein IIb/IIIa receptor antagonist, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery. It is a glycoprotein IIb/IIIa inhibitor. While abciximab has a short plasma half-life, due to its strong affinity for its receptor on the platelets, it may occupy some receptors for weeks. In practice, platelet aggregation gradually returns to normal about 96 to 120 hours after discontinuation of the drug. E27-E35 Abciximab is made from the Fab Fragment of an immunoglobulin that targets the glycoprotein IIb/IIIa receptor on the platelet membrane.

Reactivity

Human

Storage

Store at -20¡ãC for long-term storage. Store at 2-8¡ãC for up to one month. Avoid freeze/thaw cycles.