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antibody from antibodies-online
Targeting: LRP1
A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN358150 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) (pSer452) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S452 of human LPR1.
- Description
- Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer452
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-kappaB-dependent manner.
LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion.
Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone.
Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.
LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.
Yu G, Rux AH, Ma P, Bdeir K, Sachais BS
Blood 2005 May 1;105(9):3545-51
Blood 2005 May 1;105(9):3545-51
LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion.
Spijkers PP, da Costa Martins P, Westein E, Gahmberg CG, Zwaginga JJ, Lenting PJ
Blood 2005 Jan 1;105(1):170-7
Blood 2005 Jan 1;105(1):170-7
Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone.
Niemeier A, Kassem M, Toedter K, Wendt D, Ruether W, Beisiegel U, Heeren J
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005 Feb;20(2):283-93
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005 Feb;20(2):283-93
Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.
Cam JA, Zerbinatti CV, Li Y, Bu G
The Journal of biological chemistry 2005 Apr 15;280(15):15464-70
The Journal of biological chemistry 2005 Apr 15;280(15):15464-70
LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.
Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, Zlokovic BV
Neuron 2004 Aug 5;43(3):333-44
Neuron 2004 Aug 5;43(3):333-44
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