ABIN1673497

antibody from antibodies-online

Targeting: TSHR LGR3

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673497

Provider

antibodies-online

Product name

anti-Thyroid Stimulating Hormone Receptor (TSHR) (N-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the N-terminal of human TSHRImmunogen affinity purified.

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Association of the TSHR gene with Graves' disease: the first disease specific locus.

Dechairo BM, Zabaneh D, Collins J, Brand O, Dawson GJ, Green AP, Mackay I, Franklyn JA, Connell JM, Wass JA, Wiersinga WM, Hegedus L, Brix T, Robinson BG, Hunt PJ, Weetman AP, Carey AH, Gough SC
European journal of human genetics : EJHG 2005 Nov;13(11):1223-30

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An insertion in the human thyrotropin receptor critical for high affinity hormone binding.

Wadsworth HL, Chazenbalk GD, Nagayama Y, Russo D, Rapoport B
Science (New York, N.Y.) 1990 Sep 21;249(4975):1423-5

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Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.

Akamizu T, Ikuyama S, Saji M, Kosugi S, Kozak C, McBride OW, Kohn LD
Proceedings of the National Academy of Sciences of the United States of America 1990 Aug;87(15):5677-81