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Immunocytochemistry
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- V2182 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- L1CAM Antibody
- Antibody type
- Monoclonal
- Antigen
- A homogenous suspension of 16 week human fetal brain was used as the immunogen for this L1CAM antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- UJ127
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the L1CAM antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson's disease.
miR-21-3p is a positive regulator of L1CAM in several human carcinomas.
L1CAM stimulates glioma cell motility and proliferation through the fibroblast growth factor receptor.
Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion.
Targeting cancer stem cells through L1CAM suppresses glioma growth.
Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells.
Shi M, Liu C, Cook TJ, Bullock KM, Zhao Y, Ginghina C, Li Y, Aro P, Dator R, He C, Hipp MJ, Zabetian CP, Peskind ER, Hu SC, Quinn JF, Galasko DR, Banks WA, Zhang J
Acta neuropathologica 2014 Nov;128(5):639-50
Acta neuropathologica 2014 Nov;128(5):639-50
miR-21-3p is a positive regulator of L1CAM in several human carcinomas.
Doberstein K, Bretz NP, Schirmer U, Fiegl H, Blaheta R, Breunig C, Müller-Holzner E, Reimer D, Zeimet AG, Altevogt P
Cancer letters 2014 Nov 28;354(2):455-66
Cancer letters 2014 Nov 28;354(2):455-66
L1CAM stimulates glioma cell motility and proliferation through the fibroblast growth factor receptor.
Mohanan V, Temburni MK, Kappes JC, Galileo DS
Clinical & experimental metastasis 2013 Apr;30(4):507-20
Clinical & experimental metastasis 2013 Apr;30(4):507-20
Soluble L1CAM promotes breast cancer cell adhesion and migration in vitro, but not invasion.
Li Y, Galileo DS
Cancer cell international 2010 Sep 15;10:34
Cancer cell international 2010 Sep 15;10:34
Targeting cancer stem cells through L1CAM suppresses glioma growth.
Bao S, Wu Q, Li Z, Sathornsumetee S, Wang H, McLendon RE, Hjelmeland AB, Rich JN
Cancer research 2008 Aug 1;68(15):6043-8
Cancer research 2008 Aug 1;68(15):6043-8
Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells.
Sebens Müerköster S, Werbing V, Sipos B, Debus MA, Witt M, Grossmann M, Leisner D, Kötteritzsch J, Kappes H, Klöppel G, Altevogt P, Fölsch UR, Schäfer H
Oncogene 2007 Apr 26;26(19):2759-68
Oncogene 2007 Apr 26;26(19):2759-68
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Supportive validation
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- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free L1CAM Antibody (clone UJ127). Confirmation of Integrity and Purity of the Antibody.
