ACTN1

gene product
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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127 antibodies from 21 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
36 antibodies
Santa Cruz Biotechnology
1 antibody
Aviva Systems Biology
3 antibodies
Novus Biologicals
9 antibodies
GeneTex
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Atlas Antibodies
1 antibody
OriGene
1 antibody
Abnova Corporation
4 antibodies
LifeSpan BioSciences, Inc.
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Biorbyt
4 antibodies
Proteintech Group
1 antibody
Thermo Fisher Scientific Pierce
4 antibodies
Cell Signaling Technology, Inc
2 antibodies
RabMAbs
5 antibodies
Acris Antibodies GmbH
4 antibodies
Creative Biomart
10 antibodies
Enzo Life Sciences
2 antibodies
EMD Millipore
2 antibodies
Bioworld Technology, Inc
1 antibody
Sigma-Aldrich
5 antibodies
United States Biological
2 antibodies