ACTN1

gene product
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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260 antibodies from 28 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
OriGene
7 antibodies
Santa Cruz Biotechnology
1 antibody
antibodies-online
63 antibodies
Abnova Corporation
4 antibodies
Aviva Systems Biology
4 antibodies
Novus Biologicals
13 antibodies
GeneTex
4 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
30 antibodies
Biorbyt
30 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
3 antibodies
R&D Systems
2 antibodies
Bioworld Technology, Inc
2 antibodies
Enzo Life Sciences
2 antibodies
Cell Signaling Technology, Inc
3 antibodies
Acris Antibodies GmbH
6 antibodies
RabMAbs
5 antibodies
NovoPro Bioscience Inc.
4 antibodies
NSJ Bioreagents
1 antibody
MyBioSource
14 antibodies
Abgent
4 antibodies
United States Biological
39 antibodies
Abiocode, Inc.
3 antibodies
Creative Biolabs
3 antibodies
St John's Laboratory
4 antibodies
EMD Millipore
2 antibodies
Sigma-Aldrich
5 antibodies