BS6010

antibody from Bioworld Technology, Inc

Targeting: MTM1

Immunohistochemistry

Antibody data

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Validation data

Product number: BS6010 - Provider product page
Provider: Bioworld Technology, Inc
Product name: Myotubularin polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human Myotubularin.
Description: Human MTM1, a 603 amino-acid protein, is mutated in myotubular myopathy. The largely related protein hMTMR2 is found mutated in a recessive form of Charcot-Marie-tooth neuropathy. Myotubularin is primarily a lipid phosphatase that acts on hosphatidylinositol 3-monophosphate and is involved in the regulation of the phosphatidylinositol 3-kinase (PI 3-kinase) pathway and membrane trafficking. Wildtype myotubularin can directly dephosphorylate PI 3-P and PI 4-P in vitro. Thus, it decreases PI 3-P levels by down-regulating PI 3-K activity and by facilitating the degradation of PI 3-P.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

MTM1 protein structure - BS6010 shown in red.