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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN361971 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN361971, RRID:AB_10954452
- Product name
- anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (pThr645) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr645 (P-A-T (p) -I-K) derived from Human STAT6. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pThr645
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references The IL-4 receptor: signaling mechanisms and biologic functions.
Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha.
Essential role of Stat6 in IL-4 signalling.
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.
An interleukin-4-induced transcription factor: IL-4 Stat.
Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE
Annual review of immunology 1999;17:701-38
Annual review of immunology 1999;17:701-38
Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha.
Malabarba MG, Rui H, Deutsch HH, Chung J, Kalthoff FS, Farrar WL, Kirken RA
The Biochemical journal 1996 Nov 1;319 ( Pt 3):865-72
The Biochemical journal 1996 Nov 1;319 ( Pt 3):865-72
Essential role of Stat6 in IL-4 signalling.
Takeda K, Tanaka T, Shi W, Matsumoto M, Minami M, Kashiwamura S, Nakanishi K, Yoshida N, Kishimoto T, Akira S
Nature 1996 Apr 18;380(6575):627-30
Nature 1996 Apr 18;380(6575):627-30
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.
Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JL, Pierce JH, Keegan AD, Nelms K
Molecular and cellular biology 1995 Jun;15(6):3336-43
Molecular and cellular biology 1995 Jun;15(6):3336-43
An interleukin-4-induced transcription factor: IL-4 Stat.
Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McKnight SL
Science (New York, N.Y.) 1994 Sep 16;265(5179):1701-6
Science (New York, N.Y.) 1994 Sep 16;265(5179):1701-6
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