FBXO17

This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Description

F-box protein 17

Tissue specificity

Tissue enhanced (liver)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

19 (38941401 - 38975742)

Ensembl ID

ENSG00000269190  (ver. 103.38)

Orthologs

Mouse Fbxo17: ENSMUSG00000030598

UniProt

Q96EF6

neXtProt

NX_Q96EF6

Human splice variants
Mouse splice variants

Protein structure