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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN967945 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 94-208) antibody
- Antibody type
- Monoclonal
- Antigen
- Human FADD
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 94-208
- Isotype
- IgG
- Antibody clone number
- 1
- Vial size
- 150 μg
- Concentration
- 250 μg/ml
- Storage
- -20°C
Submitted references Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex.
c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis.
Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
MacFarlane M, Harper N, Snowden RT, Dyer MJ, Barnett GA, Pringle JH, Cohen GM
Oncogene 2002 Oct 3;21(44):6809-18
Oncogene 2002 Oct 3;21(44):6809-18
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex.
Micheau O, Thome M, Schneider P, Holler N, Tschopp J, Nicholson DW, Briand C, Grütter MG
The Journal of biological chemistry 2002 Nov 22;277(47):45162-71
The Journal of biological chemistry 2002 Nov 22;277(47):45162-71
c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis.
Chang DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, Peter ME, Yang X
The EMBO journal 2002 Jul 15;21(14):3704-14
The EMBO journal 2002 Jul 15;21(14):3704-14
Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.
Wieder T, Essmann F, Prokop A, Schmelz K, Schulze-Osthoff K, Beyaert R, Dörken B, Daniel PT
Blood 2001 Mar 1;97(5):1378-87
Blood 2001 Mar 1;97(5):1378-87
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM
Cell 1995 May 19;81(4):505-12
Cell 1995 May 19;81(4):505-12
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