ABIN966032

antibody from antibodies-online

Targeting: EGFR ERBB, ERBB1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966032

Provider

antibodies-online

Product name

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1070) antibody

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of serine 1070 (R-Y-SP-S-D).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100ug

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation.

Feinmesser RL, Wicks SJ, Taverner CJ, Chantry A
The Journal of biological chemistry 1999 Jun 4;274(23):16168-73

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Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor.

Gamou S, Shimizu N
FEBS letters 1995 Jan 3;357(2):161-4

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Calphostin-C stimulates epidermal growth factor receptor phosphorylation and internalization via light-dependent mechanism.

Gamou S, Shimizu N
Journal of cellular physiology 1994 Jan;158(1):151-9

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Epidermal growth factor receptor threonine and serine residues phosphorylated in vivo.

Heisermann GJ, Gill GN
The Journal of biological chemistry 1988 Sep 15;263(26):13152-8