BS4617

antibody from Bioworld Technology, Inc
Targeting: PTK2 FADK, FAK, FAK1, PPP1R71
Provider product page for BS4617
Western blot
Immunohistochemistry

Antibody data

Product number
BS4617 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FAK (phospho Y397) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human FAK around the phosphorylation site of Serine 397.
Description
Focal adhesion kinase was initially identified as a major 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src-encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique as compared to other proteins described to date. Localization of p125 by immunofluorescence suggests that it is primarily found in cellular focal adhesions leading to its designation as focal adhesion kinase (FAK). FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PTK2 protein structure - BS4617 shown in red.