ABIN120732

antibody from antibodies-online

Targeting: SYK

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN120732

Provider

antibodies-online

Product name

anti-Spleen tyrosine Kinase (SYK) (AA 5-360) antibody

Antibody type

Monoclonal

Description

Affinity Chromatography on Protein A

Reactivity

Human, Mouse, Rat

Host

Mouse

Epitope

AA 5-360

Isotype

IgG

Antibody clone number

SYK-01

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.Shelf Life: one year from despatch.

References

Submitted references

Topography of plasma membrane microdomains and its consequences for mast cell signaling.

Heneberg P, Lebduska P, Dráberová L, Korb J, Dráber P
European journal of immunology 2006 Oct;36(10):2795-806

---

A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fc epsilon receptor.

Hálová I, Dráberová L, Dráber P
International immunology 2002 Feb;14(2):213-23

---

Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation.

Parravicini V, Gadina M, Kovarova M, Odom S, Gonzalez-Espinosa C, Furumoto Y, Saitoh S, Samelson LE, O'Shea JJ, Rivera J
Nature immunology 2002 Aug;3(8):741-8

---

Vav1 regulates phospholipase cgamma activation and calcium responses in mast cells.

Manetz TS, Gonzalez-Espinosa C, Arudchandran R, Xirasagar S, Tybulewicz V, Rivera J
Molecular and cellular biology 2001 Jun;21(11):3763-74

---

Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcepsilon receptor I aggregation.

Kovárová M, Tolar P, Arudchandran R, Dráberová L, Rivera J, Dráber P
Molecular and cellular biology 2001 Dec;21(24):8318-28

---

The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH(2)-terminal kinase 1.

Arudchandran R, Brown MJ, Peirce MJ, Song JS, Zhang J, Siraganian RP, Blank U, Rivera J
The Journal of experimental medicine 2000 Jan 3;191(1):47-60

---

Requirement for a negative charge at threonine 60 of the FcRgamma for complete activation of Syk.

Swann PG, Odom S, Zhou YJ, Szallasi Z, Blumberg PM, Draber P, Rivera J
The Journal of biological chemistry 1999 Aug 13;274(33):23068-77

---

Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fc epsilon receptors.

Amoui M, Dráberová L, Tolar P, Dráber P
European journal of immunology 1997 Jan;27(1):321-8

---

Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells.

Tolar P, Dráberová L, Dráber P
European journal of immunology 1997 Dec;27(12):3389-97