ABIN196757

antibody from antibodies-online

Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN196757

Provider

antibodies-online

Product name

anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr1248) antibody

Antibody type

Polyclonal

Description

Immunoaffinity chromatography

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pTyr1248

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells.

Ramsauer VP, Carraway CA, Salas PJ, Carraway KL
The Journal of biological chemistry 2003 Aug 8;278(32):30142-7

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Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27(kip), but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways.

Jepson S, Komatsu M, Haq B, Arango ME, Huang D, Carraway CA, Carraway KL
Oncogene 2002 Oct 24;21(49):7524-32

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ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.

Ren Z, Schaefer TS
The Journal of biological chemistry 2002 Oct 11;277(41):38486-93

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Prognostic and predictive significance of ErbB-2 breast tumor levels measured by enzyme immunoassay.

Eppenberger-Castori S, Kueng W, Benz C, Caduff R, Varga Z, Bannwart F, Fink D, Dieterich H, Hohl M, Müller H, Paris K, Schoumacher F, Eppenberger U
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001 Feb 1;19(3):645-56