ABIN966277

antibody from antibodies-online

Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966277

Provider

antibodies-online

Product name

anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized non-phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine 1221/1222 (N-L-YP-YP -W).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human

Host

Rabbit

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Memo mediates ErbB2-driven cell motility.

Marone R, Hess D, Dankort D, Muller WJ, Hynes NE, Badache A
Nature cell biology 2004 Jun;6(6):515-22

---

ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.

Ren Z, Schaefer TS
The Journal of biological chemistry 2002 Oct 11;277(41):38486-93

---

Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.

Klapper LN, Waterman H, Sela M, Yarden Y
Cancer research 2000 Jul 1;60(13):3384-8

---

The duration of phorbol-inducible ErbB2 tyrosine dephosphorylation parallels that of receptor endocytosis rather than threonine-686 phosphorylation: implications for the physiological role of protein kinase C in growth factor receptor signalling.

Ouyang X, Gulliford T, Epstein RJ
Carcinogenesis 1998 Nov;19(11):2013-9

---

Adjacent carboxyterminal tyrosine phosphorylation events identify functionally distinct ErbB2 receptor subsets: implications for molecular diagnostics.

Ouyang X, Huang GC, Chantry A, Epstein RJ
Experimental cell research 1998 Jun 15;241(2):467-75