103020

antibody from BioLegend

Targeting: CD44 CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1

Antibody data

Submit

Validation data

Product number: 103020 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#103020, RRID:AB_493683
Product name: Pacific Blue™ anti-mouse/human CD44 [IM7]
Antibody type: Monoclonal
Antigen: Dexamethasone-induced myeloid leukemia M1 cells
Description: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
Reactivity: Human, Mouse, Bovine, Canine, Feline, Horse, Porcine, Simian
Host: Rat
Conjugate: Blue dye
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The CD44 antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

CD44 protein structure - 103020 shown in red.