FGF1

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]

Description

fibroblast growth factor 1 (acidic)

Protein family

-

Chromosome

5:q31.3 (141971743 - 142077617)

Ensembl ID

ENSG00000113578  (ver. 69.37)

Orthologs

Mouse Fgf1: ENSMUSG00000036585

Human splice variants
Mouse splice variants