AATK

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Description

apoptosis-associated tyrosine kinase

Protein family

Enzymes, Kinases, Membrane proteins predicted by MDM

Chromosome

17:q25.3 (79091095 - 79139877)

Ensembl ID

ENSG00000181409  (ver. 69.37)

Orthologs

Mouse Aatk: ENSMUSG00000025375

Human splice variants
Mouse splice variants