ICMT

This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]

Description

isoprenylcysteine carboxyl methyltransferase

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Potential transmembrane proteins, Potentially secreted proteins

Chromosome

1:p36.31 (6281253 - 6296032)

Ensembl ID

ENSG00000116237  (ver. 71.37)

Orthologs

Mouse Icmt: ENSMUSG00000039662

Human splice variants
Mouse splice variants