ACAD8

This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency. [provided by RefSeq, Nov 2009]

Description

acyl-CoA dehydrogenase family, member 8

Protein family

Mapped to UniProt SWISS-PROT, Potential transmembrane proteins, Potentially secreted proteins

Chromosome

11:q25 (134123389 - 134135749)

Ensembl ID

ENSG00000151498  (ver. 71.37)

Orthologs

Mouse Acad8: ENSMUSG00000031969

Human splice variants
Mouse splice variants