VTCN1

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Description

V-set domain containing T cell activation inhibitor 1

Protein family

Membrane proteins predicted by MDM

Chromosome

1:p13.1 (117686209 - 117753556)

Ensembl ID

ENSG00000134258  (ver. 69.37)

Orthologs

Mouse Vtcn1: ENSMUSG00000051076

Human splice variants
Mouse splice variants