AKT3

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Description

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

Protein family

Enzymes, Kinases

Chromosome

1 (243651535 - 244014381)

Ensembl ID

ENSG00000117020  (ver. 69.37)

Orthologs

Mouse Akt3: ENSMUSG00000019699

Human splice variants
Mouse splice variants