IKBKG
gene productFIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]
Featured antibodies
 Thermo Fisher Scientific Pierce |
PA5-28606 | 0 references | Polyclonal |
WB  IF IH
|
Antibodies
Filters
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider