DACH2

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Description

dachshund homolog 2 (Drosophila)

Protein family

-

Chromosome

X:q21.2 (85403462 - 86087607)

Ensembl ID

ENSG00000126733  (ver. 69.37)

Orthologs

Mouse Dach2: ENSMUSG00000025592

Human splice variants
Mouse splice variants