CCRL2

This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008]

Description

chemokine (C-C motif) receptor-like 2

Protein family

GPCRs excl olfactory receptors, Membrane proteins predicted by MDM

Chromosome

3:p21.31 (46448654 - 46451014)

Ensembl ID

ENSG00000121797  (ver. 69.37)

Orthologs

Mouse Ccrl2: ENSMUSG00000043953

Human splice variants
Mouse splice variants