SLC9A3R2

This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Description

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

Protein family

Mapped to UniProt SWISS-PROT, Transporters

Chromosome

16:p13.3 (2075357 - 2089027)

Ensembl ID

ENSG00000065054  (ver. 71.37)

Orthologs

Mouse Slc9a3r2: ENSMUSG00000002504

Human splice variants
Mouse splice variants