Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- V3043 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Major Vault Protein Antibody
- Antibody type
- Monoclonal
- Antigen
- Proteins precipitated from human breast cancer MCF-7 cells were used as the immunogen for the Major Vault Protein antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 1032
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the Major Vault Protein antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Major vault protein may affect nonhomologous end-joining repair and apoptosis through Ku70/80 and bax downregulation in cervical carcinoma tumors.
Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell.
Lloret M, Lara PC, Bordón E, Fontes F, Rey A, Pinar B, Falcón O
International journal of radiation oncology, biology, physics 2009 Mar 15;73(4):976-9
International journal of radiation oncology, biology, physics 2009 Mar 15;73(4):976-9
Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell.
Abbondanza C, Rossi V, Roscigno A, Gallo L, Belsito A, Piluso G, Medici N, Nigro V, Molinari AM, Moncharmont B, Puca GA
The Journal of cell biology 1998 Jun 15;141(6):1301-10
The Journal of cell biology 1998 Jun 15;141(6):1301-10
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of T98G cell lysate with Major Vault Protein antibody (clone 1032). Observed molecular weight: 104~110kDa.
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of formalin-fixed, paraffin-embedded human testicular carcinoma stained with Major Vault Protein antibody (1032).
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of formalin-fixed, paraffin-embedded human breast carcinoma stained with Major Vault Protein antibody (1032).