10-3002-F

antibody from ABEOMICS Inc.

Targeting: TLR6 CD286

Antibody data

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Validation data

Product number: 10-3002-F - Provider product page
Provider: ABEOMICS Inc.
Product name: Anti-TLR6 Antibody-
Antibody type: Monoclonal
Description: TLR6 (Toll-Like Receptors 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 forms heterodimers with TLR1 and TLR2, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 in co-operation with TLR6 trigger inflammatory responses via activation of NF-kappaB, which regulates the transcription of inflammatory molecules. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles)-induced inflammatory responses. Upon silencing, TLR6 significantly inhibited the pro-inflammatory cytokine levels, reactive nitrogen species generation and inducible nitric oxide synthase expression.
Reactivity: Human
Host: Mouse
Conjugate: Green dye
Antigen sequence: A partial length recombinant TLR6 p rotein (amino acids 280-512) was us ed as the immunogen for this antibo dy.
Isotype: IgG
Antibody clone number: ABM1B50
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing

TLR6 protein structure - 10-3002-F shown in red.