609701

antibody from BioLegend

Targeting: SSRP1 FACT80

Western blot (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Chromatin Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

609701

Provider

BioLegend

Proper citation

BioLegend Cat#609701, RRID:AB_315730

Product name

Purified anti-SSRP1

Antibody type

Monoclonal

Antigen

Recombinant (partial)

Description

SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D1 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

25 µg

Concentration

0.5 mg/ml

Storage

Upon receipt, store undiluted at 4° C.