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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Western blot [2]
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- Product number
- MAB2366 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2366, RRID:AB_10550390
- Product name
- BIRC5 monoclonal antibody, clone 60.11
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant BIRC5.
- Isotype
- IgG
- Antibody clone number
- 60.11
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival.
The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney.
Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer.
Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression.
Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression.
Brocardo M, Lei Y, Tighe A, Taylor SS, Mok MT, Henderson BR
The Journal of biological chemistry 2008 Feb 29;283(9):5950-9
The Journal of biological chemistry 2008 Feb 29;283(9):5950-9
The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney.
Lechler P, Wu X, Bernhardt W, Campean V, Gastiger S, Hackenbeck T, Klanke B, Weidemann A, Warnecke C, Amann K, Engehausen D, Willam C, Eckardt KU, Rödel F, Wiesener MS
The American journal of pathology 2007 Nov;171(5):1483-98
The American journal of pathology 2007 Nov;171(5):1483-98
Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer.
Ryan B, O'Donovan N, Browne B, O'Shea C, Crown J, Hill AD, McDermott E, O'Higgins N, Duffy MJ
British journal of cancer 2005 Jan 17;92(1):120-4
British journal of cancer 2005 Jan 17;92(1):120-4
Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression.
Xu ZX, Zhao RX, Ding T, Tran TT, Zhang W, Pandolfi PP, Chang KS
The Journal of biological chemistry 2004 Jan 16;279(3):1838-44
The Journal of biological chemistry 2004 Jan 16;279(3):1838-44
Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression.
Allen SM, Florell SR, Hanks AN, Alexander A, Diedrich MJ, Altieri DC, Grossman D
Cancer research 2003 Feb 1;63(3):567-72
Cancer research 2003 Feb 1;63(3):567-72
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BIRC5 in HeLa whole cell extract using BIRC5 monoclonal antibody, clone 60.11 (Cat # MAB2366).
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BIRC5 on cells that were transfected with the pCMV6-ENTRY control (1) or pCMV6-ENTRY BIRC5 cDNA for 48 hrs and lysed (2) using BIRC5 monoclonal antibody, clone 60.11 (Cat # MAB2366). Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC5.
