PAB2548

antibody from Abnova Corporation

Targeting: PHB PHB1

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB2548

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB2548, RRID:AB_1578681

Product name

PHB polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of PHB.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis.

Gregory-Bass RC, Olatinwo M, Xu W, Matthews R, Stiles JK, Thomas K, Liu D, Tsang B, Thompson WE
International journal of cancer 2008 May 1;122(9):1923-30

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The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.

Ross JA, Nagy ZS, Kirken RA
The Journal of biological chemistry 2008 Feb 22;283(8):4699-713

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Assignment of the human prohibitin gene (PHB) to chromosome 17 and identification of a DNA polymorphism.

White JJ, Ledbetter DH, Eddy RL Jr, Shows TB, Stewart DA, Nuell MJ, Friedman V, Wood CM, Owens GA, McClung JK
Genomics 1991 Sep;11(1):228-30

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of PHB1 (arrow) using rabbit PHB polyclonal antibody (Cat # PAB2548). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PHB1 gene (Lane 2) (Origene Technologies).