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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Immunohistochemistry [3]
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- Product number
- NB110-59934 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-59934, RRID:AB_2164493
- Product name
- Mouse Monoclonal Prohibitin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. This is specific to 30kD protein known as Prohibitin. Prohibitin is an evolutionarily conserved protein located in the innermembrane of mitochondria. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. This antibody cross reacts with mouse, rat, and pig.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 6 ml
- Storage
- Store at 4C.
Submitted references Immune surveillance properties of human NK cell-derived exosomes.
SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH.
Up-regulation of prohibitin 1 is involved in the proliferation and migration of liver cancer cells.
Lugini L, Cecchetti S, Huber V, Luciani F, Macchia G, Spadaro F, Paris L, Abalsamo L, Colone M, Molinari A, Podo F, Rivoltini L, Ramoni C, Fais S
Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 15;189(6):2833-42
Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 15;189(6):2833-42
SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH.
Pellegrini L, Pucci B, Villanova L, Marino ML, Marfe G, Sansone L, Vernucci E, Bellizzi D, Reali V, Fini M, Russo MA, Tafani M
Cell death and differentiation 2012 Nov;19(11):1815-25
Cell death and differentiation 2012 Nov;19(11):1815-25
Up-regulation of prohibitin 1 is involved in the proliferation and migration of liver cancer cells.
Xu Z, Wu J, Zha X
Science China. Life sciences 2011 Feb;54(2):121-7
Science China. Life sciences 2011 Feb;54(2):121-7
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Prohibitin Antibody (II-14-10) [NB110-59934] - Formalin fixed paraffin embedded human heart stained with Prohibitin antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prohibitin Antibody (II-14-10) [NB110-59934] - Staining of liver hepato cellular carcinoma.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prohibitin Antibody (II-14-10) - IHC-Prediluted [NB110-59934] - Formalin fixed paraffin embedded liver hepato cellular carcinoma stained with Prohibitin antibody (NB110-59934).
