370510

antibody from BioLegend

Targeting: GZMK PRSS, TRYP2

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

370510

Provider

BioLegend

Proper citation

BioLegend Cat#370510, RRID:AB_2632848

Product name

APC anti-human Granzyme K

Antibody type

Monoclonal

Description

Granzyme K is a 29 kD serine protease found in cytoplasmic granules of cytotoxic lymphocytes and NK cells. Granzyme K is thought to induce cell death and lysis in response to non-self antigens on the cell surface by cleaving nucleosome assembly protein SET. Granzyme K is upregulated in several diseases associated with inflammation including arthritis, atherosclerosis, and asthma.

Reactivity

Human

Host

Mouse

Conjugate

Red dye

Antibody clone number

GM26E7

Vial size

100 tests

Storage

2°C-8°C

Handling

Ambient RT

Flow cytometry

Supportive validation

Submitted by

BioLegend (provider)

Main image

Experimental details

Human peripheral blood lymphocytes were stained with CD8 FITC, fixed, permeabilized, and intracellularly stained with anti-human Granzyme K antibody (clone GM26E7) APC (top) or mouse IgG1, κ APC isotype control.

Conjugate

Red dye