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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Product number
- BAF532 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal TGF-beta RII Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse TGF-beta RII in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human (rh) TGF-beta RII and less than 2% cross-reactivity with recombinant mouse TGF-beta RI and rhTGF-beta RIII is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Biotin
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references TGF-β prevents T follicular helper cell accumulation and B cell autoreactivity.
TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expression.
CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential.
Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice.
McCarron MJ, Marie JC
The Journal of clinical investigation 2014 Oct;124(10):4375-86
The Journal of clinical investigation 2014 Oct;124(10):4375-86
TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expression.
Ouyang W, Oh SA, Ma Q, Bivona MR, Zhu J, Li MO
Immunity 2013 Aug 22;39(2):335-46
Immunity 2013 Aug 22;39(2):335-46
CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential.
Radulovic K, Manta C, Rossini V, Holzmann K, Kestler HA, Wegenka UM, Nakayama T, Niess JH
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):2001-13
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):2001-13
Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice.
Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B
The Journal of biological chemistry 2003 Jul 4;278(27):25109-19
The Journal of biological chemistry 2003 Jul 4;278(27):25109-19
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