FAB241P-100

antibody from R&D Systems

Targeting: TGFBR2 MFS2, TBR-ii, TBRII

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

FAB241P-100

Provider

R&D Systems

Product name

Human TGF-beta RII PE-conjugated Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. This antibody has been validated by flow cytometry on TGF-beta RII-transfected cells only. In contrast to Catalog # FAB2411P, minimal staining of PBMC lymphocytes was observed with this antibody.

Reactivity

Human

Host

Mouse

Antigen sequence

P37173.2


Isotype

IgG

Antibody clone number

25508

Vial size

100 Tests

Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

References

Submitted references

CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGFβ / GARP-mediated mechanism.

Miller MM, Petty CS, Tompkins MB, Fogle JE
Virology journal 2014 Jan 18;11:7

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Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation.

Lages CS, Suffia I, Velilla PA, Huang B, Warshaw G, Hildeman DA, Belkaid Y, Chougnet C
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1835-48

Flow cytometry

Supportive validation

Submitted by

R&D Systems (provider)

Main image

Experimental details

Detection of TGF-beta RII in NS0 Mouse Cell Line transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII PE-conjugated Monoclonal Antibody (Catalog # FAB241P, filled histogram) or isotype control antibody (Catalog # IC002P, open histo-gram). View our protocol for Staining Membrane-associated Proteins.