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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Product number
- ABIN117950 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cullin 4A (CUL4A) (N-Term), (AA 1-20) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to amino acids 1-20 of Human Cul4A (N-terminus) coupled coupled to KLH.
- Description
- Serum
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- N-Term,AA 1-20
- Vial size
- 0.1 mL
- Concentration
- 85.0 mg/mL (by Refractometry)
- Storage
- Store undiluted at 2-8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint.
The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.
Single-tooth implants in the maxillary incisor region with immediate provisionalization: 2-year prospective study.
CUL-4A is critical for early embryonic development.
Ubiquitin and its kin: how close are the family ties?
Cullin 4A associates with the UV-damaged DNA-binding protein DDB.
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers.
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins.
Higa LA, Mihaylov IS, Banks DP, Zheng J, Zhang H
Nature cell biology 2003 Nov;5(11):1008-15
Nature cell biology 2003 Nov;5(11):1008-15
The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.
Groisman R, Polanowska J, Kuraoka I, Sawada J, Saijo M, Drapkin R, Kisselev AF, Tanaka K, Nakatani Y
Cell 2003 May 2;113(3):357-67
Cell 2003 May 2;113(3):357-67
Single-tooth implants in the maxillary incisor region with immediate provisionalization: 2-year prospective study.
Groisman M, Frossard WM, Ferreira HM, de Menezes Filho LM, Touati B
Practical procedures & aesthetic dentistry : PPAD 2003 Mar;15(2):115-22, 124; quiz 126
Practical procedures & aesthetic dentistry : PPAD 2003 Mar;15(2):115-22, 124; quiz 126
CUL-4A is critical for early embryonic development.
Li B, Ruiz JC, Chun KT
Molecular and cellular biology 2002 Jul;22(14):4997-5005
Molecular and cellular biology 2002 Jul;22(14):4997-5005
Ubiquitin and its kin: how close are the family ties?
Jentsch S, Pyrowolakis G
Trends in cell biology 2000 Aug;10(8):335-42
Trends in cell biology 2000 Aug;10(8):335-42
Cullin 4A associates with the UV-damaged DNA-binding protein DDB.
Shiyanov P, Nag A, Raychaudhuri P
The Journal of biological chemistry 1999 Dec 10;274(50):35309-12
The Journal of biological chemistry 1999 Dec 10;274(50):35309-12
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y
Molecular cell 1999 Apr;3(4):535-41
Molecular cell 1999 Apr;3(4):535-41
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
Michel JJ, Xiong Y
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers.
Chen LC, Manjeshwar S, Lu Y, Moore D, Ljung BM, Kuo WL, Dairkee SH, Wernick M, Collins C, Smith HS
Cancer research 1998 Aug 15;58(16):3677-83
Cancer research 1998 Aug 15;58(16):3677-83
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM
Cell 1996 Jun 14;85(6):829-39
Cell 1996 Jun 14;85(6):829-39
Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins.
Mathias N, Johnson SL, Winey M, Adams AE, Goetsch L, Pringle JR, Byers B, Goebl MG
Molecular and cellular biology 1996 Dec;16(12):6634-43
Molecular and cellular biology 1996 Dec;16(12):6634-43
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