ABIN374097

antibody from antibodies-online

Targeting: STAP2 BKS, STAP-2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN374097

Provider

antibodies-online

Product name

anti-Signal Transducing Adaptor Family Member 2 (STAP2) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Peptide from the C Terminus of the protein sequence according to NP_060190.2, NP_001013863.1 Genename: STAP2

Description

Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Reactivity

Human, Mouse, Rat

Host

Goat

Antigen sequence

C-ELQKKLEKRRALEH


Epitope

C-Term

Vial size

0.1 mg

Concentration

0.5 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells.

Ikeda O, Mizushima A, Sekine Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T
Cancer science 2011 Apr;102(4):756-61

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Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.

Ikeda O, Sekine Y, Mizushima A, Nakasuji M, Miyasaka Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T
The Journal of biological chemistry 2010 Dec 3;285(49):38093-103

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STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation.

Ikeda O, Miyasaka Y, Sekine Y, Mizushima A, Muromoto R, Nanbo A, Yoshimura A, Matsuda T
Biochemical and biophysical research communications 2009 Jun 19;384(1):71-5

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Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells.

Sekine Y, Ikeda O, Tsuji S, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 15;183(12):7966-74