360604

antibody from BioLegend

Targeting: CCR8 CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

360604

Provider

BioLegend

Proper citation

BioLegend Cat#360604, RRID:AB_2562615

Product name

PE anti-human CCR8

Antibody type

Monoclonal

Antigen

Human CCR8-transfectants

Description

CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Antibody clone number

L263G8

Vial size

100 tests

Storage

2°C-8°C

Handling

Ambient RT

Flow cytometry

Supportive validation

Submitted by

BioLegend (provider)

Main image

Experimental details

Human peripheral blood lymphocytes were stained with CD3 APC and CCR8 (clone L263G8) PE (top) or mouse IgG2a, κ PE isotype control (bottom).

Conjugate

Yellow dye