ABIN968077

antibody from antibodies-online

Targeting: ITGA5 CD49e, FNRA

Western blot (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ABIN968077

Provider

antibodies-online

Product name

anti-Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) (AA 853-1002) antibody

Antibody type

Monoclonal

Antigen

Human Integrin alpha5

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

AA 853-1002

Isotype

IgG

Antibody clone number

1

Vial size

50 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions.

Sottile J, Hocking DC
Molecular biology of the cell 2002 Oct;13(10):3546-59

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Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration.

Alahari SK, Lee JW, Juliano RL
The Journal of cell biology 2000 Dec 11;151(6):1141-54

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Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains.

Aplin AE, Short SM, Juliano RL
The Journal of biological chemistry 1999 Oct 29;274(44):31223-8

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Functional role of N-glycosylation in alpha 5 beta 1 integrin receptor. De-N-glycosylation induces dissociation or altered association of alpha 5 and beta 1 subunits and concomitant loss of fibronectin binding activity.

Zheng M, Fang H, Hakomori S
The Journal of biological chemistry 1994 Apr 22;269(16):12325-31

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Functional role of the cytoplasmic domain of the integrin alpha 5 subunit.

Bauer JS, Varner J, Schreiner C, Kornberg L, Nicholas R, Juliano RL
The Journal of cell biology 1993 Jul;122(1):209-21