53-9775-80

antibody from Invitrogen Antibodies
Targeting: COX4I1 COX4, COX4-1
Provider product page for 53-9775-80
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
53-9775-80 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-COX4 Monoclonal Antibody (IB52C31H10), Alexa Fluor 488, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The IB52C31H10 monoclonal antibody recognizes human COX IV. COX IV, also known as cytochrome c oxidase (COX) or Complex IV, is the terminal complex of the electron transport chain. COX IV is encoded by nuclear DNA and localized to the inner mitochondrial membrane. COX IV functions in energy metabolism and shuttles electrons from cytochrome c to oxygen. Dysfunction in COX IV is associated with increased production of reactive oxygen species and cellular toxicity. Genetic defects in COX IV results in severe, often fatal metabolic disorders that primarily affect tissues with high energy demands such as heart, brain, and muscle. Applications Reported: This IB52C31H10 antibody has been reported for use in microscopy, immunohistochemical staining, immunocytochemistry, immunohistochemical staining of frozen tissue sections, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections. Applications Tested: This IB52C31H10 antibody has been tested by immunocytochemistry of MeOH-fixed human cells and can be used at less than or equal to 10 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Antibody clone number
IB52C31H10
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
4° C, store in dark, DO NOT FREEZE!
COX4I1 protein structure - 53-9775-80 shown in red.