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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB9911P-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-21R PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human IL-21 R in direct ELISAs. In direct ELISAs, this antibody does not cross-react with recombinant human (rh)IL-2 R beta or rmIL-21 R.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q9HBE5- Isotype
- IgG
- Antibody clone number
- 152512
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-γ-dependent epidermal hyperplasia.
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription.
Heterogeneous expression and function of IL-21R and susceptibility to IL-21-mediated apoptosis in follicular lymphoma cells.
Regulating human Th17 cells via differential expression of IL-1 receptor.
Effect of IL-21 on NK cells derived from different umbilical cord blood populations.
Sarra M, Caruso R, Cupi ML, Monteleone I, Stolfi C, Campione E, Diluvio L, Mazzotta A, Botti E, Chimenti S, Costanzo A, MacDonald TT, Pallone F, Monteleone G
Journal of immunology (Baltimore, Md. : 1950) 2011 May 1;186(9):5435-42
Journal of immunology (Baltimore, Md. : 1950) 2011 May 1;186(9):5435-42
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Llinàs L, Lázaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P
Immunology letters 2011 Jan 30;134(2):113-21
Immunology letters 2011 Jan 30;134(2):113-21
Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription.
Liu Y, Yang B, Ma J, Wang H, Huang F, Zhang J, Chen H, Wu C
Immunology 2011 Apr;132(4):540-8
Immunology 2011 Apr;132(4):540-8
Heterogeneous expression and function of IL-21R and susceptibility to IL-21-mediated apoptosis in follicular lymphoma cells.
de Totero D, Capaia M, Fabbi M, Croce M, Meazza R, Cutrona G, Zupo S, Loiacono F, Truini M, Ferrarini M, Ferrini S
Experimental hematology 2010 May;38(5):373-83
Experimental hematology 2010 May;38(5):373-83
Regulating human Th17 cells via differential expression of IL-1 receptor.
Lee WW, Kang SW, Choi J, Lee SH, Shah K, Eynon EE, Flavell RA, Kang I
Blood 2010 Jan 21;115(3):530-40
Blood 2010 Jan 21;115(3):530-40
Effect of IL-21 on NK cells derived from different umbilical cord blood populations.
Perez SA, Mahaira LG, Sotiropoulou PA, Gritzapis AD, Iliopoulou EG, Niarchos DK, Cacoullos NT, Kavalakis YG, Antsaklis AI, Sotiriadou NN, Baxevanis CN, Papamichail M
International immunology 2006 Jan;18(1):49-58
International immunology 2006 Jan;18(1):49-58
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of IL-21 R in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human IL-21 R PE-conjugated Monoclonal Antibody (Catalog # FAB9911P) and Mouse Anti-Human CD19 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB4867F). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.
