Explore
Validate
LearnNBP1-60046
antibody from Novus Biologicals
Targeting: MUC1
ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [4]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NBP1-60046 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-60046, RRID:AB_11031251
- Product name
- Rabbit Polyclonal MUC1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. The immunogen for this antibody has 100% homology to human MUC1 isoforms S2, E2, 9, F, T10, 5, Y, Y-LSP, 8, 4, 3, 2, 1 and J13.
- Reactivity
- Human, Mouse, Rat, Bovine, Goat, Guinea Pig, Porcine, Rabbit
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation.
MUC1 downregulation promotes TNF-α-induced necroptosis in human bronchial epithelial cells via regulation of the RIPK1/RIPK3 pathway.
MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease.
2,4-Thiazolidinedione Treatment Improves the Innate Immune Response in Dairy Goats with Induced Subclinical Mastitis.
Ballester B, Milara J, Cortijo J
Oncotarget 2020 Apr 14;11(15):1306-1320
Oncotarget 2020 Apr 14;11(15):1306-1320
MUC1 downregulation promotes TNF-α-induced necroptosis in human bronchial epithelial cells via regulation of the RIPK1/RIPK3 pathway.
Zhang H, Ji J, Liu Q, Xu S
Journal of cellular physiology 2019 Sep;234(9):15080-15088
Journal of cellular physiology 2019 Sep;234(9):15080-15088
MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease.
Milara J, Díaz-Platas L, Contreras S, Ribera P, Roger I, Ballester B, Montero P, Cogolludo Á, Morcillo E, Cortijo J
Respiratory research 2018 Nov 20;19(1):226
Respiratory research 2018 Nov 20;19(1):226
2,4-Thiazolidinedione Treatment Improves the Innate Immune Response in Dairy Goats with Induced Subclinical Mastitis.
Rosa F, Osorio JS, Trevisi E, Yanqui-Rivera F, Estill CT, Bionaz M
PPAR research 2017;2017:7097450
PPAR research 2017;2017:7097450
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: MUC-1 Antibody [NBP1-60046] - Total protein from mouse 3T3 cells and human HeLa cells, stomach and colon was separated on a 4-15% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-MUC-1 in 1% non-fat milk in TBST and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MUC1 Antibody [NBP1-60046] - Human kidney lysate tissue at an antibody concentration of 4-8ug/ml.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MUC1 Antibody [NBP1-60046] - Human stomach.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MUC1 Antibody [NBP1-60046] - Pig stomach.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MUC1 Antibody [NBP1-60046] - Pig stomach.
