ABIN401407

antibody from antibodies-online

Targeting: THRA AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN401407

Provider

antibodies-online

Product name

anti-Thyroid Hormone Receptor, alpha (THRA) (Isoform 1), (N-Term) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to a region near the amino terminus of Human THRA isoform 1 protein . Genename: THRA

Description

Immunoaffinity Chromatography

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Isoform 1,N-Term

Isotype

IgG

Vial size

25 μL

Concentration

0.89 mg/mL (by UV absorbance at 280 nm)

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor.

Ying H, Araki O, Furuya F, Kato Y, Cheng SY
Molecular and cellular biology 2007 Mar;27(6):2359-71

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Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.

Nascimento AS, Dias SM, Nunes FM, Aparício R, Ambrosio AL, Bleicher L, Figueira AC, Santos MA, de Oliveira Neto M, Fischer H, Togashi M, Craievich AF, Garratt RC, Baxter JD, Webb P, Polikarpov I
Journal of molecular biology 2006 Jul 14;360(3):586-98

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Pituitary resistance to thyroid hormone syndrome is associated with T3 receptor mutants that selectively impair beta2 isoform function.

Wan W, Farboud B, Privalsky ML
Molecular endocrinology (Baltimore, Md.) 2005 Jun;19(6):1529-42

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Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gene.

Laudet V, Begue A, Henry-Duthoit C, Joubel A, Martin P, Stehelin D, Saule S
Nucleic acids research 1991 Mar 11;19(5):1105-12