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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN499111 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) (AA 580-640) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to unique epitope on SREBF2 selected from mid-region,amino acids 580-640Remarks: The SREBF2 peptide was post-synthetically covalently modified to achievedesired antigenicity
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 0.1 mg
- Concentration
- 0.64-0.72 mg/ml (lot specific)
- Storage
- Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis.
Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.
Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins.
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element.
Najafi-Shoushtari SH, Kristo F, Li Y, Shioda T, Cohen DE, Gerszten RE, Näär AM
Science (New York, N.Y.) 2010 Jun 18;328(5985):1566-9
Science (New York, N.Y.) 2010 Jun 18;328(5985):1566-9
Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.
Zeng L, Liao H, Liu Y, Lee TS, Zhu M, Wang X, Stemerman MB, Zhu Y, Shyy JY
The Journal of biological chemistry 2004 Nov 19;279(47):48801-7
The Journal of biological chemistry 2004 Nov 19;279(47):48801-7
Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins.
Weber LW, Boll M, Stampfl A
World journal of gastroenterology : WJG 2004 Nov 1;10(21):3081-7
World journal of gastroenterology : WJG 2004 Nov 1;10(21):3081-7
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.
Horton JD, Goldstein JL, Brown MS
The Journal of clinical investigation 2002 May;109(9):1125-31
The Journal of clinical investigation 2002 May;109(9):1125-31
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
Horton JD, Shimomura I, Brown MS, Hammer RE, Goldstein JL, Shimano H
The Journal of clinical investigation 1998 Jun 1;101(11):2331-9
The Journal of clinical investigation 1998 Jun 1;101(11):2331-9
SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element.
Hua X, Yokoyama C, Wu J, Briggs MR, Brown MS, Goldstein JL, Wang X
Proceedings of the National Academy of Sciences of the United States of America 1993 Dec 15;90(24):11603-7
Proceedings of the National Academy of Sciences of the United States of America 1993 Dec 15;90(24):11603-7
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