ABIN658778

antibody from antibodies-online

Targeting: ECSIT SITPEC

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN658778

Provider

antibodies-online

Product name

anti-ECSIT Homolog (Drosophila) (ECSIT) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Other

Reactivity

Human

Host

Rabbit

Vial size

0.1 mg

Concentration

0.25 mg/ml

References

Submitted references

Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly.

Vogel RO, Janssen RJ, van den Brand MA, Dieteren CE, Verkaart S, Koopman WJ, Willems PH, Pluk W, van den Heuvel LP, Smeitink JA, Nijtmans LG
Genes & development 2007 Mar 1;21(5):615-24

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Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.

Xiao C, Shim JH, Klüppel M, Zhang SS, Dong C, Flavell RA, Fu XY, Wrana JL, Hogan BL, Ghosh S
Genes & development 2003 Dec 1;17(23):2933-49

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ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.

Kopp E, Medzhitov R, Carothers J, Xiao C, Douglas I, Janeway CA, Ghosh S
Genes & development 1999 Aug 15;13(16):2059-71