BS2983

antibody from Bioworld Technology, Inc
Targeting: HNF4A HNF4, MODY, MODY1, NR2A1, TCF14
Provider product page for BS2983
Western blot
Immunohistochemistry

Antibody data

Product number
BS2983 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2983, RRID:AB_1663168
Product name
HNF4Ï« (K307) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 280-330 of Human HNF4Ï«.
Description
Hepatocyte nuclear factor 4Ï« (HNF4Ï«) is a transcription factor that belongs to the steroid hormone receptor superfamily and is enriched in liver. HNF4Ï«, in association with PGC-1Ï«, activates gluconeogenic genes such as phosphoenolpyruvate carboxykinase and glucose-6-phosphatase genes in fasted livers. Conditional knockout of the HNF4Ï« gene in the mouse liver destroys lipid homeostasis and leads to lipid accumulation in the liver and a reduction of serum cholesterol and triglyceride levels. Mutations in HNF4Ï« have been linked to maturity-onset diabetes of the young (MODY).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HNF4A protein structure - BS2983 shown in red.